1Department of Neurosurgery, Peking University First Hospital; and.
2Department of the Interventional Neuroradiology, Beijing Tiantan Hospital Affiliated to the Capital Medical University, Beijing, China.
Neurosurg Focus. 2019 Feb 1;46(2):E8. doi: 10.3171/2018.11.FOCUS18360.
OBJECTIVESymptomatic steno-occlusion of the proximal vertebral artery (VA) or subclavian artery (ScA) heralds a poor prognosis and high risk of stroke recurrence despite medical therapy, including antiplatelet or anticoagulant drugs. In some cases, the V2 segment of the cervical VA is patent and perfused via collateral vessels. The authors describe 7 patients who were successfully treated by external carotid artery (ECA)-saphenous vein (SV)-VA bypass.METHODSSeven cases involving symptomatic patients were retrospectively studied: 3 cases of V1 segment occlusion, 2 cases of severe in-stent restenosis in the V1 segment, and 2 cases of occlusion of the proximal ScA. All patients underwent ECA-SV-VA bypass. The ECA was isolated and retracted, and the anterior wall of the transverse foramen was unroofed. The VA was exposed, and then the 2 ends of the SV were anastomosed to the VA and ECA in an end-to-side fashion.RESULTSSurgical procedures were all performed as planned, with no intraoperative complications. There were 2 postoperative complications (severe laryngeal edema in one case and shoulder weakness in another), but both patients recovered fully and measures were taken to minimize laryngeal edema and its effects in subsequent cases. All patients experienced improvement of their symptoms. No new neurological deficits were reported. Postoperative angiography demonstrated that the anastomoses were all patent, and analysis of follow-up data (range of follow-up 12-78 months) revealed no further ischemic events in the vertebrobasilar territory.CONCLUSIONSThe ECA-SV-VA bypass is a useful treatment for patients who suffer medically refractory ischemic events in the vertebrobasilar territory when the proximal part of the VA or ScA is severely stenosed or occluded but the V2 segment of the cervical VA is patent.
尽管进行了包括抗血小板或抗凝药物在内的药物治疗,椎动脉(VA)或锁骨下动脉(ScA)近端狭窄性闭塞的症状仍预示着预后不良和卒中复发风险高。在某些情况下,VA 的颈 2 段(V2 段)通过侧支血管保持通畅并得到灌注。作者描述了 7 例通过颈外动脉(ECA)-隐静脉(SV)-VA 旁路手术成功治疗的患者。
回顾性研究了 7 例有症状的患者:3 例 V1 段闭塞,2 例 V1 段严重支架内再狭窄,2 例近端 ScA 闭塞。所有患者均接受 ECA-SV-VA 旁路手术。游离并牵开 ECA,切开横突孔前壁,显露 VA,然后将 SV 的 2 端以端侧吻合的方式分别与 VA 和 ECA 吻合。
所有手术均按计划进行,无术中并发症。术后有 2 例并发症(1 例严重喉水肿,1 例肩部无力),但 2 例患者均完全恢复,后续病例中采取措施尽量减轻喉水肿及其影响。所有患者的症状均得到改善,未出现新的神经功能缺损。术后血管造影显示吻合口均通畅,随访(12-78 个月)分析显示椎基底动脉区域无进一步缺血事件。
当 VA 或 ScA 近端严重狭窄或闭塞但颈段 VA 的 V2 段通畅时,ECA-SV-VA 旁路是治疗药物难治性椎基底动脉区域缺血事件的有效方法。