Witt Chance M, Cha Yong-Mei
Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Card Electrophysiol Clin. 2019 Mar;11(1):141-146. doi: 10.1016/j.ccep.2018.11.012. Epub 2018 Dec 24.
Cardiac resynchronization therapy has been proven to be clearly beneficial for patients with heart failure, a prolonged QRS duration, and a left ventricular ejection fraction ≤35%. Ejection fraction cutoff, however, is arbitrary and very likely excludes many patients who could benefit from cardiac resynchronization. This article describes the major detrimental effects of left bundle branch block and summarizes the data regarding the potential beneficial effects of cardiac resynchronization in patients with a left ventricular ejection fraction greater than 35%.
心脏再同步治疗已被证明对心力衰竭、QRS时限延长且左心室射血分数≤35%的患者明显有益。然而，射血分数的临界值是人为设定的，很可能会排除许多可能从心脏再同步治疗中获益的患者。本文描述了左束支传导阻滞的主要有害影响，并总结了关于左心室射血分数大于35%的患者进行心脏再同步治疗潜在有益效果的数据。
