[Methodologic bases for the mathematical planning of experiments in sanitary chemical research on polymeric building materials].

The most simple approaches and principles of orthogonal mathematic planning of one-, two- and three-factor experiments are discussed. The matrices of planning and the way of calculating the coefficients of regression of linear and quadratic models are given, as well as the way of control the rate of compliance of the established mathematical model with the experimental data by its average quadratic deviation, which should not surpass the error of the experiment. In spite developed in connection with the sanitary-chemical studies of the polymer building materials, the mathematical planning of the experiment can be applied also in other fields of hygiene, medicine etc. if the respective conditions are present.