Popivanova I, Berakha R
Probl Khig. 1988;13:36-48.
The most simple approaches and principles of orthogonal mathematic planning of one-, two- and three-factor experiments are discussed. The matrices of planning and the way of calculating the coefficients of regression of linear and quadratic models are given, as well as the way of control the rate of compliance of the established mathematical model with the experimental data by its average quadratic deviation, which should not surpass the error of the experiment. In spite developed in connection with the sanitary-chemical studies of the polymer building materials, the mathematical planning of the experiment can be applied also in other fields of hygiene, medicine etc. if the respective conditions are present.
讨论了单因素、双因素和三因素实验的正交数学规划的最简单方法和原则。给出了规划矩阵以及线性和二次模型回归系数的计算方法，还给出了通过平均二次偏差控制所建立的数学模型与实验数据的符合率的方法，该平均二次偏差不应超过实验误差。尽管该方法是结合聚合物建筑材料的卫生化学研究而开发的，但如果存在相应条件，实验的数学规划也可应用于卫生、医学等其他领域。
