Schanzer M C, Jacobson E D, Dafny N
Neuroendocrinology. 1978;25(6):329-42. doi: 10.1159/000122754.
Permanent semi-microelectrodes were implanted in the ventromedial hypothalamus (VMH), lateral hypothalamus (LH), amygdala (AMYG), medial forebrain bundle (MFB), anterior hypothalamus (AH), inferior colliculus (IC), and caudate nucleus (CN). Average evoked responses were recorded simultaneously from the above sites in freely behaving rats before and after administration of pentagastrin (100 microgram/kg), secretin 1 microgram/kg or cholecystokinin octapeptide (CCK-OP) (1 microgram/kg) in search of satiety signal. Gastrin and secretin had little effect while it appears that CCK may perform a regulatory function in a neurohumoral feedback mechanism.
将永久性半微电极植入腹内侧下丘脑（VMH）、外侧下丘脑（LH）、杏仁核（AMYG）、内侧前脑束（MFB）、下丘脑前部（AH）、下丘（IC）和尾状核（CN）。在自由活动的大鼠中，于注射五肽胃泌素（100微克/千克）、促胰液素1微克/千克或八肽胆囊收缩素（CCK-OP）（1微克/千克）之前和之后，同时记录上述部位的平均诱发反应，以寻找饱腹感信号。胃泌素和促胰液素影响不大，而胆囊收缩素似乎可能在神经体液反馈机制中发挥调节作用。
