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多种心血管危险因素提示1级高血压患者存在心血管疾病。

Multiple Cardiovascular Risk Factors Indicate Cardiovascular Disease in Stage 1 Hypertension.

作者信息

DeMarzo Arthur P

机构信息

Dermed Diagnostics Inc, 2S 558 White Birch Lane, Wheaton, IL, 60189, USA.

出版信息

High Blood Press Cardiovasc Prev. 2019 Apr;26(2):135-137. doi: 10.1007/s40292-019-00304-w. Epub 2019 Feb 5.

DOI:10.1007/s40292-019-00304-w
PMID:30719630
Abstract

In November 2017, the American College of Cardiology and American Heart Association released new guidelines on hypertension that lowered the blood pressure (BP) definition of stage 1. Impedance cardiography (ICG) has shown that ventricular, vascular, and hemodynamic abnormalities are prevalent in adults over 40 years of age with at least 2 cardiovascular (CV) risk factors. This suggests that all stage 1 hypertension patients with multiple CV risk factors, over 40 years of age, have earlystage CV disease and should be treated. For many of these patients, ICG testing has shown low cardiac index with high systemic vascular resistance or vice versa. If only BP is measured, these significant extremes in hemodynamics would be unknown. With ICG data, drug selection and titration can be customized based on the abnormal underlying mechanisms to rapidly control BP while reducing adverse side effects and preventing progression of CV disease.

摘要

2017年11月,美国心脏病学会和美国心脏协会发布了关于高血压的新指南,该指南降低了1期高血压的血压定义。阻抗心动图(ICG)显示,在40岁以上具有至少2种心血管(CV)危险因素的成年人中,心室、血管和血流动力学异常普遍存在。这表明,所有40岁以上具有多种CV危险因素的1期高血压患者都患有早期CV疾病,应接受治疗。对于许多这类患者,ICG检测显示心脏指数低而全身血管阻力高,反之亦然。如果仅测量血压,这些显著的血流动力学极端情况将不为人知。有了ICG数据,可根据潜在的异常机制定制药物选择和滴定,以在减少不良副作用和预防CV疾病进展的同时迅速控制血压。

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