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[基于甲状腺腐蚀标本扫描电子显微镜数据的正常大鼠甲状腺及运动不足时的微循环床]

[The microcirculatory bed of the normal rat thyroid and during hypokinesia based on scanning electron microscopy data on corrosion preparations].

作者信息

Polianskaia L I, Mironov A A, Mironov V A

出版信息

Arkh Anat Gistol Embriol. 1988 Nov;95(11):51-6.

PMID:3071987
Abstract

In 12 mature white rats with body mass of 180-230 g, that are kept in tight pencil-cases for 10, 30 and 90 days (3 rats make the control), by means of scanning electron microscopy of corrosive preparations reorganizations of three-dimensional spatial organization of the thyroid microcirculatory bed are studied. In intact animals single-layered network of the perifollicular capillaries consists of widely anastomotic blood microvessels and makes 68 +/- 7% of the follicular surface. At hypokinesia (Hk) lasting for 10 days, the perifollicular capillaries are sharply dilated, the capillary network area makes 74 +/- 4%. A large amount of processes appear on the capillary walls. On the 30th day of Hk unequal distribution of capillaries on the follicular surface is noted, that is heterogeneity in organization of the perifollicular capillary networks is manifested. In 90 days of Hk reduction of the capillaries is recorded, rarefied pericapillary network prevails, twistedness of the capillaries is clearly manifested, their complex branching decreases. The capillary network area makes 54 +/- 3% of the follicular area. A large amount of pin-shaped protrusions of the capillary wall appear.

摘要

在12只体重为180 - 230克的成年白鼠中,将它们置于狭窄的铅笔盒中分别饲养10天、30天和90天(3只作为对照),通过对腐蚀制剂的扫描电子显微镜研究甲状腺微循环床三维空间组织的重组情况。在完整动物中,滤泡周毛细血管的单层网络由广泛吻合的血液微血管组成,占滤泡表面的68±7%。在持续10天的运动不足(Hk)情况下,滤泡周毛细血管急剧扩张,毛细血管网络面积占74±4%。毛细血管壁上出现大量突起。在运动不足的第30天,注意到滤泡表面毛细血管分布不均,即滤泡周毛细血管网络组织存在异质性。在运动不足90天时,记录到毛细血管减少,稀疏的毛细血管周网络占主导,毛细血管扭曲明显,其复杂分支减少。毛细血管网络面积占滤泡面积的54±3%。毛细血管壁出现大量针状突起。

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