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ELEMENT TRIAL: study protocol for a randomized controlled trial on endoscopic ultrasound-guided biliary drainage of first intent with a lumen-apposing metal stent vs. endoscopic retrograde cholangio-pancreatography in the management of malignant distal biliary obstruction.ELEMENT 试验:一项随机对照试验的研究方案,旨在比较内镜超声引导下胆管引流术(使用 lumen-apposing 金属支架)与内镜逆行胰胆管造影术(ERCP)在治疗恶性远端胆道梗阻中的疗效。
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本文引用的文献

1
EUS-Guided Biliary Drainage Versus ERCP for the Primary Palliation of Malignant Biliary Obstruction: A Multicenter Randomized Clinical Trial.超声内镜引导下胆道引流与 ERCP 治疗恶性胆道梗阻的初次减黄作用:一项多中心随机临床试验。
Am J Gastroenterol. 2018 Jul;113(7):987-997. doi: 10.1038/s41395-018-0122-8. Epub 2018 Jul 2.
2
Consensus guidelines on the optimal management in interventional EUS procedures: results from the Asian EUS group RAND/UCLA expert panel.共识指南:介入性超声内镜术的最佳管理:来自亚洲超声内镜专家组的 RAND/UCLA 专家小组的结果。
Gut. 2018 Jul;67(7):1209-1228. doi: 10.1136/gutjnl-2017-314341. Epub 2018 Feb 20.
3
Patient perception and preference of EUS-guided drainage over percutaneous drainage when endoscopic transpapillary biliary drainage fails: An international multicenter survey.内镜下经乳头胆管引流失败时,患者对超声内镜引导下引流与经皮引流的认知及偏好:一项国际多中心调查。
Endosc Ultrasound. 2018 Jan-Feb;7(1):48-55. doi: 10.4103/eus.eus_100_17.
4
Optimal biliary access point and learning curve for endoscopic ultrasound-guided hepaticogastrostomy with transmural stenting.经壁支架置入内镜超声引导下肝胃吻合术的最佳胆管入路点及学习曲线
Therap Adv Gastroenterol. 2017 Jan;10(1):42-53. doi: 10.1177/1756283X16671671. Epub 2016 Oct 22.
5
Efficacy and safety of EUS-guided biliary drainage in comparison with percutaneous biliary drainage when ERCP fails: a systematic review and meta-analysis.内镜超声引导下胆道引流术与经皮经肝胆道引流术在ERCP失败时的疗效及安全性比较:一项系统评价和荟萃分析
Gastrointest Endosc. 2017 May;85(5):904-914. doi: 10.1016/j.gie.2016.12.023. Epub 2017 Jan 4.
6
EUS-guided biliary drainage is infrequently used even in high-volume centers of interventional EUS.即使在介入性超声内镜检查的高容量中心,超声内镜引导下胆道引流术的使用也并不频繁。
Gastrointest Endosc. 2016 Jul;84(1):206-7. doi: 10.1016/j.gie.2016.03.020.
7
Assessment of efficacy and safety of EUS-guided biliary drainage: a systematic review.超声内镜引导下胆道引流术的疗效与安全性评估:一项系统评价
Gastrointest Endosc. 2016 Jun;83(6):1218-27. doi: 10.1016/j.gie.2015.10.033. Epub 2015 Nov 2.
8
Endoscopic Ultrasound-Guided Biliary Drainage: A Systematic Review and Meta-Analysis.内镜超声引导下胆道引流:一项系统评价与荟萃分析。
Dig Dis Sci. 2016 Mar;61(3):684-703. doi: 10.1007/s10620-015-3933-0. Epub 2015 Oct 30.
9
EUS-guided biliary drainage.超声内镜引导下胆道引流术
Gastrointest Endosc. 2015 Dec;82(6):993-1001. doi: 10.1016/j.gie.2015.06.043. Epub 2015 Sep 15.
10
Feasibility and safety of a novel dedicated device for one-step EUS-guided biliary drainage: A randomized trial.一种新型专用设备用于一步法超声内镜引导下胆道引流的可行性和安全性:一项随机试验。
J Gastroenterol Hepatol. 2015 Oct;30(10):1461-6. doi: 10.1111/jgh.13027.

超声内镜引导下胆道引流术的利用不足:东西方内镜医师的认知

The underutilization of EUS-guided biliary drainage: Perception of endoscopists in the East and West.

作者信息

Yoon Won Jae, Park Do Hyun, Choi Jun Ho, Jang Sunguk, Samarasena Jason, Lee Tae Hoon, Paik Woo Hyun, Oh Dongwook, Song Tae Jun, Choi Joon Hyuk, Hara Kazuo, Iwashita Takuji, Perez-Miranda Manuel, Lee John G, Vazquez-Sequeiros Enrique, Naitoh Itaru, Vila Juan J, Brugge William R, Takenaka Mamoru, Lee Sang Soo, Seo Dong-Wan, Lee Sung Koo, Kim Myung-Hwan

机构信息

Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.

Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

出版信息

Endosc Ultrasound. 2019 May-Jun;8(3):188-193. doi: 10.4103/eus.eus_57_18.

DOI:10.4103/eus.eus_57_18
PMID:30719996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6590002/
Abstract

BACKGROUND AND OBJECTIVES

EUS-guided biliary drainage (EUS-BD) is increasingly utilized to manage unresectable malignant biliary obstruction after a failed ERCP. However, there is no data on how endoscopists perceive EUS-BD. The aim of this study was to investigate the perception of endoscopists on EUS-BD.

PATIENTS AND METHODS

A survey questionnaire of six topics with 22 survey statements was developed. A total of 17 pancreatobiliary endoscopists (10 from East and 7 from West) were invited to survey. The participants were asked to answer the multiple choice questionnaire and give comments. The opinions of the participants for individual survey statements were assessed using 5-point Likert scale.

RESULTS

All participants completed the survey. The endoscopists had a trend to perceive EUS-BD as a procedure indicated after a failed ERCP. Various EUS-BD methods were regarded as having different efficacy and safety. The superiority of EUS-BD over percutaneous transhepatic BD (PTBD) with regard to efficacy, procedure-related adverse events, and unscheduled re-intervention was not in agreement.

CONCLUSIONS

EUS-BD was not yet perceived as the initial procedure to relieve the unresectable malignant biliary obstruction. Various EUS-BD methods were regarded as having different efficacy and safety. The superiority of EUS-BD over PTBD was not in agreement. Refining the procedure, developing dedicated devices, and gaining expertise in the procedure are necessary to popularize EUS-BD.

摘要

背景与目的

内镜超声引导下胆道引流术(EUS-BD)在经内镜逆行胰胆管造影术(ERCP)失败后用于处理不可切除的恶性胆道梗阻的应用越来越广泛。然而,关于内镜医师如何看待EUS-BD尚无相关数据。本研究的目的是调查内镜医师对EUS-BD的看法。

患者与方法

设计了一份包含6个主题、22条调查陈述的调查问卷。共邀请了17名胰腺胆道内镜医师(10名来自东方,7名来自西方)参与调查。要求参与者回答多项选择题并发表评论。使用5级李克特量表评估参与者对各调查陈述的意见。

结果

所有参与者均完成了调查。内镜医师倾向于将EUS-BD视为ERCP失败后的一种治疗手段。各种EUS-BD方法被认为具有不同的疗效和安全性。在疗效、与操作相关的不良事件及非计划再次干预方面,EUS-BD相对于经皮经肝胆道引流术(PTBD)的优势并不一致。

结论

EUS-BD尚未被视为缓解不可切除恶性胆道梗阻的首选治疗手段。各种EUS-BD方法被认为具有不同的疗效和安全性。EUS-BD相对于PTBD的优势并不一致。优化操作、开发专用设备并积累该操作的专业经验对于推广EUS-BD是必要的。