San Rafael Hospital, Cadiz, Spain.
Emek Medical Center, Afula.
J Clin Gastroenterol. 2019 Aug;53(7):530-534. doi: 10.1097/MCG.0000000000001114.
An effective bowel preparation is essential for quality colonoscopy. Inadequate preparation results in missed lesions, need for earlier repeat procedures, prolonged colonoscopy duration, an increased likelihood of adverse events, reduced patient satisfaction, and increased costs. The MOTUS GI Pure-Vu System (Tirat Carmel, Israel) is an Food and Drug Administration-cleared device designed to improve visualization in an inadequately prepared colon by facilitating intraprocedural cleaning. We evaluated the efficacy, safety, and usability of the Pure-Vu System in cleansing poorly prepared colons in human subjects.
In total, 50 patients with poorly prepared colons undergoing colonoscopy were prospectively enrolled to evaluate the Pure-Vu System at 2 clinical sites [Spain (N=41) and Israel (N=9)]. Cleansing quality was measured using the Boston Bowel Preparation Score (BBPS).
In total, 50 patients (64% male individuals), mean age 51.9±10.4 years, and mean body mass index of 26.6±3.1 were enrolled. The Pure-Vu System significantly increased the BBPS median score from 5.0 at baseline to 9.0 after the use of Pure-Vu (P<0.0001). Patients with an adequate cleansing level (BBPS≥2 in each colon segment) increased significantly from 31% (15/49) at baseline to 98% (48/49) after use of Pure-Vu (P<0.001). Cecal intubation was achieved in 48/49 (98%) patients. Colonoscopists were satisfied with the Pure-Vu System. No serious adverse events were reported.
The Pure-Vu System was found to be safe, efficacious, and easy to use in cleansing inadequately prepared colons, enabling the colonoscopist to conduct a complete examination.
有效的肠道准备对于高质量的结肠镜检查至关重要。准备不充分会导致遗漏病变、需要更早地重复操作、结肠镜检查时间延长、不良事件发生的可能性增加、患者满意度降低和成本增加。MOTUS GI Pure-Vu 系统（以色列提拉 Carmel）是一种获得美国食品和药物管理局批准的设备，旨在通过促进术中清洁来改善准备不充分的结肠的可视化效果。我们评估了 Pure-Vu 系统在人类受试者中清洁准备不充分的结肠的疗效、安全性和可用性。
共有 50 名肠道准备不充分的结肠镜检查患者前瞻性入组，在 2 个临床地点（西班牙[41 名]和以色列[9 名]）评估 Pure-Vu 系统。使用波士顿肠道准备评分（BBPS）来衡量清洁质量。
共有 50 名患者（64%为男性个体），平均年龄 51.9±10.4 岁，平均体重指数为 26.6±3.1。Pure-Vu 系统显著提高了 BBPS 中位数评分，从基线时的 5.0 提高到使用 Pure-Vu 后的 9.0（P<0.0001）。使用 Pure-Vu 后，清洁水平达到足够程度（每个结肠段的 BBPS≥2）的患者比例从基线时的 31%（49/159）显著增加到 98%（49/49）（P<0.001）。48/49（98%）名患者成功进行了盲肠插管。结肠镜医师对 Pure-Vu 系统表示满意。未报告严重不良事件。
Pure-Vu 系统在清洁准备不充分的结肠方面被发现是安全、有效且易于使用的，使结肠镜医师能够进行完整的检查。
