Razmi Robin, Magnusson Peter
Uppsala Universitet - Centrum för forskning och utveckling, Region Gävleborg Uppsala, Sweden Infektionssjukdomar - Verksamhetsområde Specialmedicin Gävle, Sweden.
Uppsala Universitet - Centrum för forskning och utveckling, Region Gävleborg/Gävle Uppsala, Sweden Uppsala Universitet - Centrum för forskning och utveckling, Region Gävleborg/Gävle Uppsala, Sweden.
Lakartidningen. 2019 Feb 5;116:FEPZ.
Infective endocarditis is an uncommon but potentially lethal disease, defined as an infectious lesion of the endocardium. The possibility of infective endocarditis should be considered in all patients with gram positive bacteremia. Particular consideration is recommended in case of Staphylococcus aureus bacteremia. Treatment consists of high doses of intravenous antibiotics, usually during four weeks, but shorter or longer treatments may be applicable based on the characteristics of the patient and the infecting pathogen. Furthermore, a significant portion of patients will require thoracic surgery in order to ensure a favorable outcome. The management of infective endocarditis is a complex challenge, requiring close collaboration between infectious disease specialists, cardiologists, thoracic surgeons, clinical physiologists, and clinical microbiologists.
感染性心内膜炎是一种罕见但可能致命的疾病,定义为心内膜的感染性病变。所有革兰氏阳性菌血症患者均应考虑感染性心内膜炎的可能性。对于金黄色葡萄球菌菌血症患者,建议格外关注。治疗包括大剂量静脉注射抗生素,通常持续四周,但根据患者特征和感染病原体情况,治疗时间可能更短或更长。此外,相当一部分患者需要进行胸外科手术以确保良好预后。感染性心内膜炎的管理是一项复杂的挑战,需要传染病专家、心脏病专家、胸外科医生、临床生理学家和临床微生物学家密切合作。