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经鼻内镜蝶腭动脉结扎术与动脉栓塞治疗难治性鼻出血的成本效益比较:长期分析。

Cost-effectiveness of trans-nasal endoscopic sphenopalatine artery ligation vs arterial embolisation for intractable epistaxis: Long-term analyses.

机构信息

Medical Information Department, University Hospital of Toulouse, Toulouse Cedex 9, France.

Unité Inserm 1027, Faculté de Médecine, National Institute for Health and Medical Research (Inserm), Toulouse, France.

出版信息

Clin Otolaryngol. 2019 Jul;44(4):511-517. doi: 10.1111/coa.13299. Epub 2019 Apr 1.

Abstract

OBJECTIVES

Trans-nasal endoscopic sphenopalatine artery ligation (TESPAL) and endovascular arterial embolisation both provide excellent success rates for intractable epistaxis. Recent economic models suggest that TESPAL could be a cost-saving strategy. Our main aim was to perform cost-effectiveness analyses on TESPAL compared with embolisation to treat patients with epistaxis.

DESIGN

We performed retrospective, monocentric, comparative analyses on patients referred to our centre and treated with embolisation or TESPAL.

SETTING

This economic evaluation was carried out from a payer's perspective (ie French National Health Insurance) within a time horizon of 12 months.

PARTICIPANTS

Thirty-seven TESPAL procedures and thirty-nine embolisation procedures to treat intractable epistaxis were used in the analyses.

MAIN OUTCOME MEASURES

The primary outcome is presented as the cost per 1% of non-recurrence. Effectiveness was defined as avoiding recurrence of epistaxis during the 1-year follow-up. Cost estimates were performed from the payer's perspective.

RESULTS

Hospitalisation costs were higher for embolisation compared with TESPAL (5972 vs 3769 euros). On average, hospitalisation costs decreased by 41% when a patient was treated by TESPAL compared with an embolisation strategy (P = 0.06). The presence of comorbidities increased hospitalisation costs by 79% (P = 0.04). TESPAL enabled 1867€ to be gained in intractable epistaxis.

CONCLUSIONS

The outcomes from our decision model confirm that TESPAL is more cost-effective for patients with intractable epistaxis.

摘要

目的

经鼻内镜蝶腭动脉结扎术(TESPAL)和血管内动脉栓塞术均能为难治性鼻出血提供极好的成功率。最近的经济模型表明,TESPAL 可能是一种节省成本的策略。我们的主要目的是对 TESPAL 与栓塞治疗鼻出血患者进行成本效益分析。

设计

我们对转诊至我们中心并接受栓塞或 TESPAL 治疗的患者进行了回顾性、单中心、对比分析。

设置

该经济评估是从支付者的角度(即法国国家健康保险)在 12 个月的时间范围内进行的。

参与者

37 例 TESPAL 手术和 39 例栓塞术用于治疗难治性鼻出血。

主要观察指标

主要结果以非复发率的每 1%的成本表示。疗效定义为在 1 年随访期间避免鼻出血复发。成本估计是从支付者的角度进行的。

结果

栓塞术的住院费用高于 TESPAL(5972 欧元比 3769 欧元)。平均而言,与栓塞策略相比,TESPAL 治疗患者的住院费用降低了 41%(P=0.06)。合并症的存在使住院费用增加了 79%(P=0.04)。TESPAL 使难治性鼻出血获得了 1867 欧元的收益。

结论

我们决策模型的结果证实,TESPAL 对难治性鼻出血患者更具成本效益。

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