Clinical pharmacokinetics of doxycycline and minocycline.
作者信息
Saivin S, Houin G
机构信息
Unité de Pharmacocinétique Clinique, CHU Purpan, Toulouse, France.
出版信息
Clin Pharmacokinet. 1988 Dec;15(6):355-66. doi: 10.2165/00003088-198815060-00001.
Abstract
Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.
摘要
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