Department of Surgery, Columbia University, New York, NY, USA.
Department of Surgery, Saint Louis University, Saint Louis, MO, USA.
Transpl Int. 2019 Jul;32(7):702-709. doi: 10.1111/tri.13408. Epub 2019 Mar 22.
Most transplant centers decline morbidly obese people for living kidney donation. Their inclusion in the living donor pool after weight loss and reversal of comorbidities by bariatric surgery could reverse the downward living donation trend. We investigated whether bariatric surgery in the morbidly obese altered their candidacy for donation, complicated their subsequent donor nephrectomy, and impacted their early postoperative outcomes in a series of 22 donors who had bariatric surgery 0.7-22 years prior to laparoscopic living donor nephrectomy. Eighteen would have been excluded from donation prior to bariatric surgery based on a body mass index (BMI) > 40. Seventeen reached a BMI < 35 after bariatric surgery. One had hypertension that resolved after bariatric surgery. Prior bariatric surgery did not influence port placement and laterality of donor nephrectomy. None required open conversion or blood transfusion. In an exploratory comparison with 37 donors with a BMI 35-40, length of stay and warm ischemic time were shorter, blood loss and postoperative complications were similar, and operative time was longer. We therefore advocate the consideration of bariatric surgery in preparation for donation in morbidly obese people since it positively alters their candidacy without major impact on the subsequent living donor nephrectomy and early outcomes.
大多数移植中心拒绝病态肥胖者进行活体肾脏捐献。通过减肥手术(减重手术)减轻体重和逆转合并症后,将他们纳入活体供者库,可能会扭转活体捐献的下降趋势。我们研究了病态肥胖者接受减重手术后,是否改变了他们的捐献资格,是否使随后的供者肾切除术变得复杂,以及对 22 名在腹腔镜活体供者肾切除术前 0.7-22 年内接受过减重手术的供者的早期术后结果是否有影响。其中 18 人在接受减重手术前,由于体重指数(BMI)>40,将被排除在捐献者之外。17 人在接受减重手术后 BMI 降到<35。1 人在减重手术后高血压得到缓解。先前的减重手术并没有影响端口的放置和供肾切除术的侧别。没有人需要开放转换或输血。在与 37 名 BMI 为 35-40 的供者进行的探索性比较中,住院时间和热缺血时间更短,出血量和术后并发症相似,手术时间更长。因此,我们主张在病态肥胖者准备捐献时考虑接受减重手术,因为它可以积极改变他们的资格,而对随后的活体供者肾切除术和早期结果没有重大影响。