Korshøj Anders Rosendal, Lukacova Slavka, Mikic Nikola, Stigaard Cortnum Søren Ole, Lassen-Ramshad Yasmin, Guldberg Trine Lignell, Severinsen Kåre Eg, Thielscher Axel, Poulsen Frantz Rom, Hedemann Sørensen Jens Christian, von Oettingen Gorm Burckhard
Ugeskr Laeger. 2019 Jan 28;181(5).
Tumor treating fields (TTFields) is a new non-invasive approach to cancer treatment. TTFields are low-intensity (1-5 V/m), intermediate frequency (150-200 kHz) alternating electric fields delivered locally to the tumour to selectively kill dividing cells and disrupt cancer growth. TTFields has proven safe and effective for newly diagnosed glioblastoma and is currently being tried for multiple other tumours. This review presents an introduction to TTFields, covering the main indications, the application method, the mechanism of action, the clinical results and the perspectives for implementation in Danish cancer treatment.
肿瘤治疗电场（TTFields）是一种新型的癌症非侵入性治疗方法。TTFields是低强度（1 - 5 V/m）、中频（150 - 200 kHz）的交变电场，局部作用于肿瘤，以选择性地杀死正在分裂的细胞并破坏肿瘤生长。TTFields已被证明对新诊断的胶质母细胞瘤安全有效，目前正在对多种其他肿瘤进行试验。本综述介绍了TTFields，涵盖了主要适应症、应用方法、作用机制、临床结果以及在丹麦癌症治疗中的应用前景。
