Wu Linxiao, Magaz Adrián, Maughan Elizabeth, Oliver Nina, Darbyshire Arnold, Loizidou Marilena, Emberton Mark, Birchall Martin, Song Wenhui
Centre for Biomaterials in Surgical Reconstruction and Regeneration, Division of Surgery & Interventional Science, University College London, London NW3 2PF, United Kingdom.
UCL Ear Institute, Royal National Throat Nose and Ear Hospital and University College London, London, United Kingdom.
Data Brief. 2019 Jan 10;22:885-902. doi: 10.1016/j.dib.2019.01.012. eCollection 2019 Feb.
This DiB article contains data related to the research article entitled "Cellular responses to thermoresponsive stiffness memory elastomer nanohybrid scaffolds by 3D-TIPS" (Wu et al., 2018). Thermoresponsive poly (urea-urethane) nanohybrid elastomer (PUU-POSS) scaffolds were implanted in rats for up to 3 months. The porous structure and tensile mechanical properties of the scaffolds are listed and compared before and after and tests. The details of the histological analysis of the explants with different initial stiffness and porous structures at various time points are presented. The images and data presented support the conclusion about the coupled effects of stiffness softening and the hierarchical porous structure modulating tissue ingrowth, vascularization and macrophage polarization in the article (Wu et al., 2018).
这篇《生物材料学报》文章包含与题为《3D-TIPS法制备的热响应性刚度记忆弹性体纳米杂化支架的细胞响应》（Wu等人，2018年）的研究文章相关的数据。将热响应性聚（脲-聚氨酯）纳米杂化弹性体（PUU-POSS）支架植入大鼠体内长达3个月。列出并比较了支架在测试前后的多孔结构和拉伸力学性能。展示了在不同时间点对具有不同初始刚度和多孔结构的外植体进行组织学分析的详细情况。所呈现的图像和数据支持了文章（Wu等人，2018年）中关于刚度软化和分级多孔结构对组织生长、血管化和巨噬细胞极化的耦合作用的结论。
