School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China.
Chem Commun (Camb). 2019 Feb 19;55(16):2348-2351. doi: 10.1039/c8cc09369e.
A reverse hydrogenolysis process has been developed for two-site coupling of 2-hydroxy-1,4-naphthoquinones with olefins to produce naphtha[2,3-b]furan-4,9-diones and hydrogen (H2). The reaction is catalyzed by commercially available Pd/C without oxidants and hydrogen acceptors, thereby providing an intrinsically waste-free approach for the synthesis of functionalized and potentially biologically relevant naphtha[2,3-b]furan-4,9-diones.
开发了一种反氢解过程，用于 2-羟基-1,4-萘醌与烯烃的双位点偶联，以生成萘并[2,3-b]呋喃-4,9-二酮和氢气（H2）。该反应由市售的 Pd/C 催化，无需氧化剂和氢气受体，从而为功能化和潜在具有生物学相关性的萘并[2,3-b]呋喃-4,9-二酮的合成提供了一种本质上无废物的方法。
