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[脂质体两性霉素B治疗巴西利什曼原虫引起的皮肤利什曼病:1例输入性病例报告]

[Liposomal amphotericin B treatment of cutaneous leishmaniasis caused by L. braziliensis: an imported case report].

作者信息

Navarrete-Dechent Cristián, Cevallos Carolina, Jercic María Isabel, Saldias-Fuentes Cristóbal, González Sergio, Labarca Jaime

机构信息

Departamento de Dermatología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Departamento Laboratorio Biomédico Nacional y de Referencia, Sección de Parasitología, Instituto de Salud Pública de Chile, Santiago, Chile.

出版信息

Rev Chilena Infectol. 2018;35(5):612-616. doi: 10.4067/s0716-10182018000500612.

DOI:10.4067/s0716-10182018000500612
PMID:30725012
Abstract

Leishmaniasis is an infection caused by protozoa of the genus Leishmania sp. and transmitted by sandfly vectors. Cutaneous leishmaniasis (CL) is the most frequent form of presentation. Clinically, chronic and painless ulcers are observed, which usually occur at the site of the sandfly bite. The diagnosis and treatment of this disease is specially challenging in non-endemic countries such as Chile, requiring the use of diverse laboratory techniques as well as the support of expert physicians. Herein we report an imported case of a healthy 42-year-old male with CL caused by L. braziliensis with successful response to liposomal amphotericin B.

摘要

利什曼病是由利什曼原虫属的原生动物引起的一种感染,通过白蛉媒介传播。皮肤利什曼病(CL)是最常见的表现形式。临床上,可观察到慢性无痛性溃疡,通常发生在白蛉叮咬部位。在智利等非流行国家,这种疾病的诊断和治疗极具挑战性,需要使用多种实验室技术以及专家医生的支持。在此,我们报告一例由巴西利什曼原虫引起的皮肤利什曼病的输入性病例,该病例为一名42岁健康男性,对脂质体两性霉素B治疗反应良好。

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Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021-A Comprehensive Review.2000年至2021年全球报告的人间非地方性利什曼病——一项全面综述
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