Department of General Surgery, Center Hospitalier Intercommunal de Créteil, 40 Avenue de Verdun, 94000, Créteil, France.
Service de Chirurgie Digestive, Hépato-Biliaire, Hôpital Henri-Mondor - AP-HP, 51 Avenue du Maréchal de Lattre de Tassigny, 94000, Créteil, France.
Obes Surg. 2019 Apr;29(4):1436-1438. doi: 10.1007/s11695-019-03751-5.
The immunosuppressive therapy for life after liver transplantation (LT) is considered as a risk factor for obesity. Seven percent of the transplanted patients develop severe or morbid obesity. The obesity induces non-alcoholic steatohepatitis (NASH), which is a major risk factor for liver cirrhosis and hepatocellular carcinoma, without forgetting the cardiovascular risk and the devastating impact of obesity on quality of life of the transplanted patients. Consequently, obesity exposes these patients to future transplant loss. Bariatric surgery has been proposed for transplant patients to reduce the obesity-related comorbidities and to improve survival. We report in this video the surgical technique of laparoscopic sleeve gastrectomy (LSG) after LT.
We have performed between 2008 and 2017 the sleeve gastrectomy (SG) after LT in nine patients. Six procedures (66%) were performed totally by laparoscopy and three by upfront laparotomy. All the patients had a standard preoperative evaluation for obesity. All the procedures were assisted by a hepatic surgeon. Postoperatively patients were transferred to the liver ICU for 24 h then to the liver unit ward.
The median BMI was 41.9 kg/m (range 38-46.1 kg/m). Median operative time was 120 min (range, 90-240 min). No intra-operative complications occurred. The median length of hospital stay was 7 days (range, 4-81 days). The postoperative course of the majority of the patients was uneventful except for one patient who develops a staple line leak.
LSG after LT is technically feasible. Larger series are needed to improve the safety of the procedure in this high-risk population.
肝移植(LT)后的免疫抑制治疗被认为是肥胖的一个风险因素。7%的移植患者会发展为严重或病态肥胖。肥胖会导致非酒精性脂肪性肝炎(NASH),这是肝硬化和肝细胞癌的一个主要危险因素,更不用说心血管风险和肥胖对移植患者生活质量的破坏性影响了。因此,肥胖使这些患者面临未来的移植失败风险。减重手术已被提议用于移植患者,以减少肥胖相关的合并症并提高生存率。我们在此视频中报告 LT 后腹腔镜袖状胃切除术(LSG)的手术技术。
我们在 2008 年至 2017 年间对 9 例 LT 后患者进行了袖状胃切除术(SG)。其中 6 例(66%)完全通过腹腔镜进行,3 例通过直接剖腹手术进行。所有患者均接受了肥胖症标准术前评估。所有手术均由肝脏外科医生协助进行。术后患者被转移到肝 ICU 24 小时,然后转到肝科病房。
中位 BMI 为 41.9kg/m²(范围 38-46.1kg/m²)。中位手术时间为 120 分钟(范围 90-240 分钟)。无术中并发症发生。中位住院时间为 7 天(范围 4-81 天)。除 1 例患者发生吻合口漏外,大多数患者的术后过程均顺利。
LT 后 LSG 在技术上是可行的。在这个高危人群中,需要更大的系列来提高该手术的安全性。