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急性创伤性缺血的高压氧评估与治疗

Acute Traumatic Ischemia Hyperbaric Evaluation and Treatment

作者信息

Torp Klaus D., Murphy-Lavoie Heather M.

机构信息

Mayo Clinic Florida

University Medical Center, LSU Medical School

Abstract

Trauma to a limb, leading to direct tissue damage plus local hypoxic conditions from resulting edema, causes acute traumatic peripheral ischemia. The trauma can vary from mild to irreversible and may involve major blood vessels and nerve injuries. For severe injuries, amputations may be required. Vascular repair and reimplantation may sometimes be required for the limb to be viable. Examples of trauma include crush injury and thermal injury. Even without major vascular injuries, the tissue damage may lead to edema formation causing tissue hypoxia, leading to more edema formation. This vicious cycle can lead to compartment syndrome within poorly compliant muscle compartments, which then presents a surgical emergency to salvage the limb. Threatened flaps also fall into the category of acute traumatic peripheral ischemia, where hyperbaric oxygen has been shown to improve ischemia. Surgical treatment and hyperbaric oxygen are not competing treatment modalities; they should be used in complementarity to provide the best outcome for the patient. Treating acute traumatic peripheral ischemia is 1 of the 13 approved hyperbaric oxygen indications by the Undersea and Hyperbaric Medical Society. It is also approved by the Centers for Medicare and Medicaid Services (CMS). The organization states that when a patient has acute traumatic peripheral ischemia or when a patient is suffering from crush injuries, and surgeons have sutured severed limbs, HBO therapy is a valuable, supplementary treatment physician may use in combination with accepted, standard, therapeutic measures when patients may lose function, limb, or life.

摘要

肢体创伤导致直接组织损伤以及由此产生的水肿引起局部缺氧状况,进而引发急性创伤性周围缺血。创伤程度可轻可重,甚至不可逆转,可能涉及主要血管和神经损伤。对于严重损伤,可能需要截肢。有时为了使肢体存活,可能需要进行血管修复和再植手术。创伤的例子包括挤压伤和热损伤。即使没有严重的血管损伤,组织损伤也可能导致水肿形成,进而引起组织缺氧,导致更多水肿形成。这种恶性循环可导致顺应性较差的肌肉间隙内出现骨筋膜室综合征,这就形成了一种需要紧急手术以挽救肢体的情况。受威胁的皮瓣也属于急性创伤性周围缺血的范畴,高压氧已被证明可改善缺血状况。手术治疗和高压氧并非相互竞争的治疗方式;它们应相互补充使用,为患者提供最佳治疗效果。治疗急性创伤性周围缺血是水下和高压氧医学协会批准的13种高压氧适应症之一。它也得到了医疗保险和医疗补助服务中心(CMS)的批准。该组织指出,当患者患有急性创伤性周围缺血或遭受挤压伤,且外科医生已缝合断肢时,高压氧治疗是一种有价值的辅助治疗方法,医生在患者可能丧失功能、肢体或生命时,可将其与公认的标准治疗措施联合使用。

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