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生理学,肌肉收缩

Physiology, Muscle Contraction

作者信息

Gash Matthew C., Kandle Patricia F., Murray Ian V., Varacallo Matthew A.

机构信息

East Tennessee St. University

St. George's University

Abstract

The physiological concept of muscle contraction is based on two variables: length and tension. In physiology, muscle shortening and muscle contraction are not synonymous. Tension within the muscle can be produced without changes in the length of the muscle, as when holding a dumbbell in the same position or holding a sleeping child in your arms. Upon termination of muscle contraction, muscle relaxation occurs, which is the return of muscle fibers to a low-tension state.  Mammals have three types of muscles: skeletal, cardiac, and smooth. Skeletal muscles are attached to bones and give the body structure and strength. Cardiac muscle comprises the walls of the heart, allowing blood to be pumped through the vasculature. Smooth muscle is found throughout the blood vessels, gastrointestinal (GI) tract, bronchioles, uterus, and bladder. Muscle contraction throughout the human body can be broken down based on muscle subtype specialization. In general, muscle fibers are classified into two large categories: striated muscle fibers and smooth muscle fibers. Striated muscle fibers contain actin and myosin filaments that power contraction and are organized into repeating arrays, called sarcomeres, with a striated microscopic appearance. Cardiac muscle tissue is a striated muscle fiber under involuntary control by the body's autonomic nervous system (ANS). Skeletal muscle tissue is a striated muscle fiber under voluntary control. Smooth muscle fibers do not contain sarcomeres but use actin and myosin contraction to constrict blood vessels and move the contents of hollow organs in the body. These fibers are under involuntary control by reflexes and the body's ANS.

摘要

肌肉收缩的生理学概念基于两个变量

长度和张力。在生理学中,肌肉缩短和肌肉收缩并非同义词。肌肉内的张力可以在肌肉长度不变的情况下产生,比如手持哑铃保持在同一位置或怀抱熟睡的孩子时。肌肉收缩终止后,会发生肌肉舒张,即肌纤维恢复到低张力状态。哺乳动物有三种肌肉:骨骼肌、心肌和平滑肌。骨骼肌附着于骨骼,赋予身体结构和力量。心肌构成心脏壁,使血液能够通过脉管系统泵出。平滑肌存在于全身的血管、胃肠道、细支气管、子宫和膀胱中。人体的肌肉收缩可根据肌肉亚型的特化进行分类。一般来说,肌纤维分为两大类:横纹肌纤维和平滑肌纤维。横纹肌纤维含有驱动收缩的肌动蛋白和肌球蛋白丝,并排列成重复的阵列,称为肌节,在显微镜下呈现出横纹外观。心肌组织是一种横纹肌纤维,受身体自主神经系统(ANS)的非自主控制。骨骼肌组织是一种受自主控制的横纹肌纤维。平滑肌纤维不含肌节,但利用肌动蛋白和肌球蛋白的收缩来收缩血管并推动体内中空器官的内容物。这些纤维受反射和身体自主神经系统的非自主控制。

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