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生物安全指南

Biosafety Guidelines

作者信息

Bayot Marlon L., Zubair Muhammad, Limaiem Faten

机构信息

Adventist University of the Philippines-College of Medicine; Coach MLB Consulting

Pakistan Kidney & Liver Institute and Research Centre - PKLI

Abstract

Biosafety guidelines are a set of policies, rules, and procedures that personnel in various facilities handling microbiological agents must follow. These agents include bacteria, viruses, parasites, fungi, prions, and other related microbial products. Institutions that must strictly adhere to biosafety guidelines include clinical and microbiological laboratories, biomedical research facilities, teaching and training laboratories, and other healthcare institutions, such as clinics, health centers, and hospitals. These guidelines aim to ensure the proper management and regulation of biosafety programs and practices implemented at all levels of the organization. The essential components of biosafety guidelines vary depending on the facility and include the following: Bio-risk assessment and identification. Specific biosafety measures encompassing codes of practice and physical infrastructure, such as laboratory design and facilities. Equipment acquisition and maintenance. Medical surveillance. Staff training. Safe handling of chemicals. Safety protocols for fire, radiation, and electricity. Additional elements, such as commissioning and certification of facilities, may also be included. Biosafety guidelines must be clear, practical, and suitable for each facility, ensuring they are accessible to all staff and regularly reviewed and updated. Although these guidelines provide guidance on biosafety practices, a safe working environment requires the commitment of each personnel to consistently adhere to them. Ongoing research in biosafety can improve the development of future guidelines.

摘要

生物安全指南是各类处理微生物制剂的设施中的人员必须遵循的一系列政策、规则和程序。这些制剂包括细菌、病毒、寄生虫、真菌、朊病毒及其他相关微生物产品。必须严格遵守生物安全指南的机构包括临床和微生物实验室、生物医学研究设施、教学和培训实验室以及其他医疗机构,如诊所、健康中心和医院。这些指南旨在确保对组织各级实施的生物安全计划和做法进行妥善管理和规范。生物安全指南的基本组成部分因设施而异,包括以下内容:生物风险评估与识别。涵盖操作规范和物理基础设施(如实验室设计和设施)的具体生物安全措施。设备采购与维护。医学监测。人员培训。化学品的安全处理。火灾、辐射和电气安全规程。还可能包括设施调试和认证等其他要素。生物安全指南必须清晰、实用且适用于每个设施,确保所有员工都能获取,并定期审查和更新。尽管这些指南为生物安全实践提供了指导,但安全的工作环境需要每位人员始终如一地遵守这些指南。生物安全方面的持续研究可以改进未来指南的制定。

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