[Structural and functional indices of disturbances of oocyte maturation in androgenized rats after induction of ovulation with pregnant mare's serum and luliberin].

The ultrastructure of oocytes from large follicles and the meiotic maturation rate of preovulatory oocytes of intact and androgenized rats were studied. The oocytes of defeminized animals were characterized by the lack of organelles and by changes of their structure. According to the rate of meiosis they were divided into two groups. The one entered the II stage metaphase earlier than in the control, the other was characterized by a slower chromosome transformation.