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乳腺癌手术后水肿手臂的斯图尔特-特里夫斯综合征

[Stewart-Treves syndrome of the edematous arm following breast cancer operation].

作者信息

Gregl A, Pavić S, Pavić Z, Schauer A, Wilke C, Zinn H

机构信息

Radiologischen Klinik Göttingen, Pathologischen Institut, Universität Göttingen.

出版信息

Z Lymphol. 1988 Dec;12(2):66-83.

PMID:3072789
Abstract

In 1948, Stewart and Treves (158) described a lymphangiosarcoma on the edematous arm for the first time with reference to six cases involving arm edema after breast cancer operation. Since their publication, a further 313 cases have become known. In 1982, with communication of one case we published a statistical compilation comprising of 248 cases (Zeitschrift für Lymphologie VI, 1982, 51-66). A statistical compilation totalling 290 observations is now presented on the basis of further studies of the older literature supplemented by observations of the last six years including two of our own cases. So far, a total of 319 single observations has become known: 21 cases of Yap et al. (182), eight cases of Oshmianskaia et al. (123) and 290 cases in the statistical compilation we have drawn up and which is the basis of this publication. By histological investigation of the tissue material taken from a female patient within six weeks (exploratory excision, radical excision), detailed information could be obtained on the histological development of the Stewart-Treves-Syndrome (STS) from a preneoplasia to a mature lymphangiosarcoma. The second female patient is a relatively rare observation of an STS of fulminant course which remained restricted to the extremity, chest wall and neighboring parts of the back during the entire course.

摘要

1948年,斯图尔特和特里夫斯(158)首次描述了发生于水肿手臂的淋巴管肉瘤,涉及6例乳腺癌手术后手臂水肿的病例。自他们发表该病例以来,又有313例病例被报道。1982年,我们报道了1例病例,并发表了一篇包含248例病例的统计汇编(《淋巴学杂志》第六卷,1982年,51 - 66页)。现在,在对旧文献进一步研究的基础上,结合过去六年的观察结果(包括我们自己的2例病例),呈现了一份总计290例观察结果的统计汇编。到目前为止,已知的单例观察结果共有319例:亚普等人(182)报道的21例,奥什缅斯卡娅等人(123)报道的8例,以及我们编制的这份作为本出版物基础的统计汇编中的290例。通过对一名女性患者在六周内获取的组织材料(探查性切除、根治性切除)进行组织学研究,可以详细了解斯图尔特 - 特里夫斯综合征(STS)从癌前病变发展到成熟淋巴管肉瘤的组织学过程。第二位女性患者是STS暴发性病程的相对罕见病例,在整个病程中病变局限于肢体、胸壁和背部相邻部位。

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