Jin Hao, Cui Min
The Second Department of General Surgery, Zhuhai People's Hospital, No. 79 of Kangning Road, Xiangzhou District, Zhuhai City, Guangdong Province, 519000, China.
Endocr Metab Immune Disord Drug Targets. 2019;19(7):936-940. doi: 10.2174/1871530319666190206212456.
For surgeons, locating parathyroid in thyroidectomy and parathyroidectomy is critical since parathyroid plays an important role in calcium balance. The fluorescence of parathyroid has already been found by researchers and the angiography equipment detecting the fluorescence of parathyroid with indocyanine green has been widely applied. Using the indocyanine green angiography and looking at the actual fluorescence of in vivo and in vitro tissues, it was possible to identify thyroid, parathyroid, lymph nodes and fat tissues during the surgical procedure. This mini-review aims to present the application of indocyanine green angiography in parathyroid detection and discusses the safety of this method.
The relevant data were searched by using the keywords "Indocyanine green," "Parathyroid," and "Identification" and "Protection" in "Pubmed," "Web of Science" and "China Knowledge Resource Integrated databases", and a manual search was done to acquire peer-reviewed articles and reports about indocyanine green.
Indocyanine green dye along with the intraoperative fluorescence imaging system is safe in detecting parathyroid and predicting postoperative hypoparathyroidism.
The conclusion suggests that indocyanine green angiography is a safe, effective and easy way to detect parathyroid glands. The conclusion will be of interest to surgeons regarding thyroidectomy and parathyroidectomy.
对于外科医生而言,在甲状腺切除术和甲状旁腺切除术中定位甲状旁腺至关重要,因为甲状旁腺在钙平衡中起着重要作用。研究人员已经发现了甲状旁腺的荧光,并且检测吲哚菁绿标记甲状旁腺荧光的血管造影设备已得到广泛应用。通过使用吲哚菁绿血管造影并观察体内和体外组织的实际荧光,在手术过程中识别甲状腺、甲状旁腺、淋巴结和脂肪组织成为可能。本综述旨在介绍吲哚菁绿血管造影在甲状旁腺检测中的应用,并讨论该方法的安全性。
在“PubMed”“科学网”和“中国知网”数据库中使用关键词“吲哚菁绿”“甲状旁腺”“识别”和“保护”搜索相关数据,并进行人工检索以获取关于吲哚菁绿的同行评议文章和报告。
吲哚菁绿染料与术中荧光成像系统相结合在检测甲状旁腺和预测术后甲状旁腺功能减退方面是安全的。
该结论表明吲哚菁绿血管造影是一种检测甲状旁腺的安全、有效且简便的方法。该结论将引起进行甲状腺切除术和甲状旁腺切除术的外科医生的兴趣。