Department of Epidemiology, INRS-Institut Armand-Frappier, Laval, Québec, Canada.
Montreal Behavioural Medicine Centre, CIUSSS-NIM, Montréal, Québec, Canada.
Br J Sports Med. 2020 Mar;54(5):272-278. doi: 10.1136/bjsports-2018-099360. Epub 2019 Feb 6.
To assess whether aerobic exercise was superior to usual care in alleviating depressive symptoms in patients living with a major non-communicable disease.
Data were obtained from online databases (PubMed, PsycINFO and SPORTDiscus) as well as from reference lists. The search and collection of eligible studies was conducted up to 18 October 2018 (PROSPERO registration number CRD42017069089).
We included interventions that compared aerobic exercise with usual care in adults who reported depressive symptoms (ie, not necessarily the clinical diagnosis of depression) and were living with a major non-communicable disease.
Twenty-four studies were included in the meta-analysis (4111 patients). Aerobic exercise alleviated depressive symptoms better than did usual care (standardised mean difference (SMD)=0.50; 95% CI 0.25 to 0.76; Grading of Recommendations Assessment, Development and Evaluation: low quality). Aerobic exercise was particularly effective in alleviating depressive symptoms in cardiac patients (SMD=0.67; 95% CI 0.35 to 0.99).
Aerobic exercise alleviated depressive symptoms in patients living with a major non-communicable disease, particularly in cardiac populations. Whether aerobic exercise treats clinically diagnosed depression was outside the scope of this study.
评估有氧运动是否优于常规护理，以缓解患有主要非传染性疾病的患者的抑郁症状。
数据来自在线数据库（PubMed、PsycINFO 和 SPORTDiscus）以及参考文献列表。对符合条件的研究的搜索和收集工作截至 2018 年 10 月 18 日（PROSPERO 注册号 CRD42017069089）。
我们纳入了将有氧运动与常规护理进行比较的干预措施，这些干预措施针对的是报告有抑郁症状（即，不一定是抑郁症的临床诊断）且患有主要非传染性疾病的成年人。
共有 24 项研究纳入荟萃分析（4111 名患者）。有氧运动比常规护理更能缓解抑郁症状（标准化均数差（SMD）=0.50；95%置信区间 0.25 至 0.76；推荐评估、制定与评价分级：低质量）。有氧运动在缓解心脏病患者的抑郁症状方面特别有效（SMD=0.67；95%置信区间 0.35 至 0.99）。
有氧运动可缓解患有主要非传染性疾病患者的抑郁症状，尤其是心脏病患者。有氧运动是否可治疗临床诊断的抑郁症不在本研究的范围内。
