Department of Orthopaedic Surgery, Hunan Provincial People's Hospital, Changsha, People's Republic of China.
Sci Rep. 2019 Feb 6;9(1):1498. doi: 10.1038/s41598-018-37727-9.
This study intends to analyze the causes on poor clinical efficacy of kyphoplasty performed in unilateral transpedicular puncture for the treatment of senile osteoporotic vertebral compression fractures. A retrospective study was conducted on a consecutive series of 70 patients who had underwent kyphoplasty performed in unilateral transpedicular puncture for the treatment of senile osteoporotic vertebral compression fractures between March 2016 to March 2017. These patients were compared for clinical data to investigate the causes on poor clinical efficacy of kyphoplasty performed in unilateral transpedicular puncture for the treatment of senile osteoporotic vertebral compression fractures. Comparison result of the indices between these patients showed that the differences in body weight, fracture type and bone cement dispersion were statistically significant. Logistic multivariate regression analysis showed body weight (OR = 0.892, p = 0.042), fracture type 2 (OR = 0.089, p = 0.020) and bone cement dispersion (OR = 4.773, p = 0.025) are risk factors for poor clinical efficacy. The results of corresponding analysis on VAS (Visual Analogue Scale), vertebral height and Cobb angle in patients with poor clinical efficacy showed that there is a correlation between them. We believe that patients' weight, dispersion degree of bone cement and fracture type of injured vertebra are the risk factors of kyphoplasty with poor clinical efficacy.
本研究旨在分析单侧经椎弓根穿刺椎体后凸成形术治疗老年骨质疏松性椎体压缩骨折临床疗效不佳的原因。回顾性分析 2016 年 3 月至 2017 年 3 月采用单侧经椎弓根穿刺椎体后凸成形术治疗的 70 例老年骨质疏松性椎体压缩骨折患者的临床资料，比较两组患者的临床资料，探讨单侧经椎弓根穿刺椎体后凸成形术治疗老年骨质疏松性椎体压缩骨折临床疗效不佳的原因。两组患者体重、骨折类型和骨水泥弥散的比较结果差异有统计学意义。Logistic 多因素回归分析显示，体重（OR=0.892，p=0.042）、骨折类型 2（OR=0.089，p=0.020）和骨水泥弥散（OR=4.773，p=0.025）是影响临床疗效的危险因素。对临床疗效差的患者 VAS（视觉模拟评分）、椎体高度和 Cobb 角进行相关分析，结果显示它们之间存在相关性。我们认为患者体重、骨水泥弥散程度和伤椎骨折类型是影响椎体后凸成形术临床疗效的危险因素。
