Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
J Anim Physiol Anim Nutr (Berl). 2019 May;103(3):813-821. doi: 10.1111/jpn.13064. Epub 2019 Feb 6.
The purpose of this article was to investigate the effects of dietary resveratrol supplementation during gestation and lactation of sows on the milk composition of sows and the fat metabolism of sucking piglets. Forty sows were allotted to two experimental treatment groups that included the following: (a) control sows (CON treatment, n = 20) fed with a corn-soybean meal control diet and (b) treatment sows (RES treatment, n = 20) fed with a control diet with addition of 300 mg/kg resveratrol. The results showed that the content of lactose in the colostrum was increased (p < 0.05) and the content of fat in 21-day milk was increased (p < 0.05) by dietary resveratrol supplementation. In the RES treatment group, the concentrations of high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), lipase activity and insulin (INS) in plasma of sucking piglets were increased (p < 0.05). In the adipose tissue, the enzyme activities of hormone-sensitive lipase (HSL), acetyl-CoA carboxylase (ACC) and lipoprotein lipase (LPL) increased significantly by RES treatment (p < 0.05), and the mRNA levels of acetyl coenzyme A-alpha (ACCα), LPL, fatty acid transport protein (FATP1) and CCAAT-enhancer-binding protein gene (C/EBPα) were higher in the RES treatment group (p < 0.05). In conclusion, resveratrol supplementation on gestational and lactating sows improved the content of lactose in the colostrum and the content of fat in milk at day 21 of lactation. In addition, resveratrol supplementation on sows increased HDL and LDL in the plasma of piglets. In piglet adipose tissue, the enzyme activity and mRNA level related to lipolysis, fatty acid uptake from circulating triacylglycerols and lipogenesis are partially improved by resveratrol supplementation on sows. These aspects affect fat metabolism in piglets.
本文旨在研究妊娠和哺乳期母猪日粮添加白藜芦醇对母猪乳成分和哺乳仔猪脂肪代谢的影响。将 40 头母猪分为两组：（a）对照组（CON 处理，n=20），饲喂玉米-豆粕基础日粮；（b）处理组（RES 处理，n=20），饲喂添加 300mg/kg 白藜芦醇的基础日粮。结果表明，日粮添加白藜芦醇可增加初乳中乳糖含量（p<0.05），增加 21 日龄乳中脂肪含量（p<0.05）。在 RES 处理组，哺乳仔猪血浆中高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、脂肪酶活性和胰岛素（INS）浓度增加（p<0.05）。在脂肪组织中，激素敏感脂肪酶（HSL）、乙酰辅酶 A 羧化酶（ACC）和脂蛋白脂肪酶（LPL）的酶活性通过 RES 处理显著增加（p<0.05），并且 RES 处理组乙酰辅酶 A-α（ACCα）、LPL、脂肪酸转运蛋白（FATP1）和 CCAAT 增强子结合蛋白基因（C/EBPα）的 mRNA 水平更高（p<0.05）。总之，妊娠和哺乳期母猪日粮添加白藜芦醇可提高初乳中乳糖含量和泌乳第 21 天乳中脂肪含量。此外，母猪日粮添加白藜芦醇可增加仔猪血浆中 HDL 和 LDL。在仔猪脂肪组织中，与脂肪分解、从循环三酰甘油摄取脂肪酸和脂肪生成相关的酶活性和 mRNA 水平部分通过母猪日粮添加白藜芦醇得到改善。这些方面影响仔猪的脂肪代谢。
