• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

最近应用于评估白癜风治疗的定量工具的临床计量学分析。

Clinimetric analysis of recently applied quantitative tools in evaluation of vitiligo treatment.

机构信息

Department of Dermatology and Andrology, Community Medicine and General Health, Benha University, Banha, Egypt.

Department of Public Health, Community Medicine and General Health, Benha University, Banha, Egypt.

出版信息

Indian J Dermatol Venereol Leprol. 2019 Sep-Oct;85(5):466-474. doi: 10.4103/ijdvl.IJDVL_63_17.

DOI:10.4103/ijdvl.IJDVL_63_17
PMID:30729924
Abstract

BACKGROUND

Vitiligo affects about 1% of the world's population, however, there is currently no universally used standardized measure to assess its response to treatment.

OBJECTIVE

To find the most effective technique for the quantitative assessment of therapeutic results in vitiligo patients.

MATERIALS AND METHODS

The study was performed in three stages: (1) Conducting an adapted Delphi survey to check current dermatologists' attitudes regarding the topic of study. (2) Conducting a pilot study that involves testing the selected digital image analysis software in the laboratory to validate future tasks. (3) The chief clinimetric study that implicates selecting actual vitiligo lesion models and evaluating them.

RESULTS

Regarding the surface area measuring techniques, the most accurate results were gained through the digital image analysis for surface area, followed by point-counting technique. The digital image analysis for color measurement was accurate and reliable in getting a percentage representation of color improvement within the vitiligo lesions, in response to therapy.

LIMITATIONS

Many dermatologists lack understanding of basic concepts about imaging techniques. The study does not include a traditional assessment method such as vitiligo area scoring index.

CONCLUSION

Our designated digital image analysis technique was able to efficiently assess the changes that occur both on surface area and the color of vitiligo lesions in response to therapy.

摘要

背景

白癜风影响着全球约 1%的人口,然而,目前还没有普遍使用的标准化方法来评估其治疗反应。

目的

寻找评估白癜风患者治疗效果的最有效技术。

材料与方法

该研究分三个阶段进行:(1)进行适应性 Delphi 调查,以检查皮肤科医生对研究主题的当前态度。(2)进行试点研究,在实验室中测试选定的数字图像分析软件,以验证未来的任务。(3)主要临床计量学研究,涉及选择实际的白癜风病变模型并进行评估。

结果

在面积测量技术方面,数字图像分析的结果最为准确,其次是点数法。数字图像分析的颜色测量在获得治疗后白癜风病变颜色改善的百分比表示方面是准确可靠的。

局限性

许多皮肤科医生对成像技术的基本概念缺乏了解。该研究不包括白癜风面积评分指数等传统评估方法。

结论

我们指定的数字图像分析技术能够有效地评估治疗后白癜风病变的面积和颜色变化。

相似文献

1
Clinimetric analysis of recently applied quantitative tools in evaluation of vitiligo treatment.最近应用于评估白癜风治疗的定量工具的临床计量学分析。
Indian J Dermatol Venereol Leprol. 2019 Sep-Oct;85(5):466-474. doi: 10.4103/ijdvl.IJDVL_63_17.
2
A pilot comparative study of topical latanoprost and tacrolimus in combination with narrow-band ultraviolet B phototherapy and microneedling for the treatment of nonsegmental vitiligo.一项关于局部用拉坦前列素和他克莫司联合窄谱紫外线B光疗及微针治疗非节段型白癜风的前瞻性对照研究。
Dermatol Ther. 2016 Nov;29(6):437-441. doi: 10.1111/dth.12383. Epub 2016 Jun 21.
3
Vitiligo nonsurgical treatment: a review of latest treatment researches.白癜风非手术治疗:最新治疗研究综述
Dermatol Ther. 2014 Sep-Oct;27(5):298-303. doi: 10.1111/dth.12143. Epub 2014 Jul 12.
4
A randomized, double-blinded, placebo-controlled trial of pseudocatalase cream and narrowband ultraviolet B in the treatment of vitiligo.一项随机、双盲、安慰剂对照的假性过氧化氢酶乳膏联合窄谱中波紫外线治疗白癜风的临床试验。
Br J Dermatol. 2009 Oct;161(4):910-7. doi: 10.1111/j.1365-2133.2009.09252.x. Epub 2009 Jun 11.
5
Determination of skin repigmentation progression.皮肤色素再沉着进展的测定。
Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:3442-5. doi: 10.1109/IEMBS.2007.4353071.
6
Independent component analysis for assessing therapeutic response in vitiligo skin disorder.用于评估白癜风皮肤疾病治疗反应的独立成分分析
J Med Eng Technol. 2009;33(2):101-9. doi: 10.1080/03091900802454459.
7
Combination of 308-nm xenon chloride excimer laser and topical calcipotriol in vitiligo.308纳米氯化氙准分子激光与外用卡泊三醇联合治疗白癜风。
J Eur Acad Dermatol Venereol. 2007 Apr;21(4):504-8. doi: 10.1111/j.1468-3083.2006.02016.x.
8
A practical method for the estimation of vitiligo surface area: a comparison between the point counting and digital planimetry techniques.一种估计白癜风表面积的实用方法:点计数法与数字平面测量技术的比较
Eur J Dermatol. 2007 Jan-Feb;17(1):30-2. doi: 10.1684/ejd.2007.0186. Epub 2007 Feb 27.
9
Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial.银杏叶治疗寻常型白癜风:一项开放标签的初步临床试验。
BMC Complement Altern Med. 2011 Mar 15;11:21. doi: 10.1186/1472-6882-11-21.
10
Controversial issues in vitiligo patients: a review of old and recent treatments.白癜风患者的争议性问题:旧治疗方法和新治疗方法的综述。
Dermatol Ther. 2019 Jan;32(1):e12745. doi: 10.1111/dth.12745. Epub 2018 Oct 21.

引用本文的文献

1
Potential of automated image analysis for the measurement of vitiligo lesions.自动图像分析在白癜风皮损测量中的应用潜力。
Front Med (Lausanne). 2025 Aug 14;12:1623408. doi: 10.3389/fmed.2025.1623408. eCollection 2025.
2
A deep learning-based hybrid artificial intelligence model for the detection and severity assessment of vitiligo lesions.一种基于深度学习的混合人工智能模型,用于白癜风皮损的检测和严重程度评估。
Ann Transl Med. 2022 May;10(10):590. doi: 10.21037/atm-22-1738.
3
Cultured epidermal autografts for treatment of stable vitiligo: Quantitative analysis of color matching with surrounding normally pigmented skin.
培养表皮自体移植治疗稳定期白癜风:与周围正常色素皮肤颜色匹配的定量分析。
J Dermatol. 2021 Sep;48(9):1405-1408. doi: 10.1111/1346-8138.16028. Epub 2021 Jun 25.
4
Mechanisms of melanocyte death in vitiligo.白癜风中黑素细胞死亡的机制。
Med Res Rev. 2021 Mar;41(2):1138-1166. doi: 10.1002/med.21754. Epub 2020 Nov 17.