Deckelbaum L I
Yale University School of Medicine, Connecticut.
Cardiol Clin. 1988 Aug;6(3):345-56.
Laser technology clearly offers new approaches to the treatment of cardiovascular disease. The ability to transmit intense laser energy through optical fibers may allow precise ablation of pathologic cardiovascular tissues. This potential has stimulated extensive research on laser vaporization of atherosclerotic plaque, or laser angioplasty. Despite the preceding several years of research, there is currently no widespread laser angioplasty system in clinical use. The goal of complete atherosclerotic plaque vaporization without damage to the underlying arterial wall still remains elusive. This article reviews multiple different approaches to the development of laser angioplasty systems. It is too early to predict if all (or any) of these systems will be perfected to the degree necessary to provide cardiologists with a safe and effective laser angioplasty system. It is also difficult to predict the effect that the technologically simpler mechanical recanalization devices and arterial stents will have on laser angioplasty development. Nevertheless, laser angioplasty remains an exciting and promising approach for intravascular recanalization by vaporization of atherosclerotic plaque.
激光技术显然为心血管疾病的治疗提供了新方法。通过光纤传输高强度激光能量的能力或许能实现对病理性心血管组织的精确消融。这种潜力激发了对动脉粥样硬化斑块激光汽化术（即激光血管成形术）的广泛研究。尽管经过了数年研究，但目前尚无广泛应用于临床的激光血管成形术系统。完全汽化动脉粥样硬化斑块而不损伤其下方动脉壁的目标仍然难以实现。本文综述了开发激光血管成形术系统的多种不同方法。现在预测这些系统中的全部（或任何一个）是否能完善到为心脏病专家提供安全有效的激光血管成形术系统所需的程度还为时过早。也很难预测技术上更简单的机械再通装置和动脉支架对激光血管成形术发展的影响。然而，激光血管成形术仍然是一种通过汽化动脉粥样硬化斑块实现血管内再通的令人兴奋且有前景的方法。
