Hunter J G, Dixon J A
West J Med. 1985 Apr;142(4):506-10.
The argon, carbon dioxide and neodymium-YAG lasers have been proposed as effective instruments for surgical procedures of the intact cardiovascular system. While argon and CO(2) lasers cause superficial (0 to 1 mm) thermal injury, the Nd:YAG laser is better suited for effecting deep thermal necrosis (3 to 4 mm). Microsurgical vessel anastomoses can be done by "tissue welding" with any of the three clinical lasers. Myocardial revascularization may be accomplished by drilling "neocapillaries" in ischemic myocardium. Endocardial resection for destroying arrhythmic pathways and removing hypertrophied septal muscle has also been successfully accomplished with laser phototherapy. Last, laser-mediated vaporization of atherosclerotic plaque in the coronary arteries and peripheral circulation may offer a percutaneous approach to the treatment of arterial occlusive disease. Cardiovascular uses of lasers are purely investigational at the current time. Much more needs to be known before widespread clinical use of lasers in the cardiovascular system can occur.
氩激光、二氧化碳激光和钕钇铝石榴石激光已被提议作为完整心血管系统外科手术的有效工具。虽然氩激光和二氧化碳激光会造成浅表(0至1毫米)热损伤,但钕钇铝石榴石激光更适合造成深度热坏死(3至4毫米)。三种临床激光中的任何一种都可通过“组织焊接”进行显微外科血管吻合。心肌血运重建可通过在缺血心肌中钻“新毛细血管”来实现。通过激光光疗也已成功完成了用于破坏心律失常传导途径和切除肥厚间隔肌的心内膜切除术。最后,激光介导的冠状动脉和外周循环中动脉粥样硬化斑块的汽化可能为治疗动脉闭塞性疾病提供一种经皮方法。目前激光在心血管方面的应用纯粹是研究性的。在激光能够在心血管系统中广泛临床应用之前,还有更多需要了解的地方。