Langmuir. 2019 Mar 5;35(9):3337-3345. doi: 10.1021/acs.langmuir.9b00014. Epub 2019 Feb 18.
Chiral nanostructures exhibited distinctive functions and attractive applications in complex biological systems, which demonstrated the subject of many outstanding research studies. In this work, various hierarchical composite film nanostructures were designed via supramolecular self-assembly using chiral amphiphilic glutamate derivatives and achiral porphyrin derivatives and their macroscopic enantioselective recognition properties were investigated. We have found that intermolecular hydrogen-bonding interactions between water (donor and acceptor) and N, N-dimethylformamide (DMF) as well as chloroform (CHCl) (acceptor only) and DMF could subtly alter the molecular packing and significantly affected the supramolecular self-assembled nanostructures and triggered circular dichroism (CD) signal reversal. Present research work exemplified a feasible method to fabricate chiral flower-like and brick-like nanostructure films in different mixed solvents and large-scale chiral transfer from the molecular level to complex structures, which also provided a facile approach to identify certain l-/d-amino acids by means of contact angle detection using present obtained self-assembled composted films.
手性纳米结构在复杂的生物体系中表现出独特的功能和诱人的应用，这成为了许多杰出研究工作的主题。在这项工作中，通过使用手性两亲性谷氨酸衍生物和非手性卟啉衍生物的超分子自组装，设计了各种分级复合膜纳米结构，并研究了它们的宏观对映选择性识别特性。我们发现，水（供体和受体）与 N，N-二甲基甲酰胺（DMF）之间以及氯仿（CHCl）（仅受体）与 DMF 之间的分子间氢键相互作用可以微妙地改变分子堆积，显著影响超分子自组装纳米结构，并引发圆二色性（CD）信号反转。目前的研究工作举例说明了一种在不同混合溶剂中制备手性花状和砖状纳米结构薄膜的可行方法，以及从分子水平到复杂结构的大规模手性转移，这也为通过使用目前获得的自组装复合材料薄膜进行接触角检测来识别某些 l-/d-氨基酸提供了一种简便的方法。
