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类风湿关节炎的放射学改变:在抗风湿药物临床治疗试验中,以关节周围骨面积测量作为结局事件

Radiological changes in rheumatoid arthritis: measurement of area of juxta-articular bone as outcome event in clinical therapeutic trials of antirheumatic drugs.

作者信息

Buchanan H M, Buchanan W W, Cockshott W P, Kamath M V, Ghista D N

机构信息

Department of Rheumatology, McMaster University Health Science Centre, Hamilton, Ontario, Canada.

出版信息

Clin Rheumatol. 1988 Dec;7(4):481-5.

PMID:3073035
Abstract

A high degree of intra - and inter - rater reproducibility was obtained in measurement of a standardized area of the head of the first right metacarpal using a precision digitizer. This instrument had an accuracy for every point digitized of 0.127 mm. Intra-rater difference between readings at approximately a month's interval showed no significant differences. The method is reasonably simple to perform and is applicable to small joints such as the proximal interphalangeal joints. The method may prove useful in following progression of joint damage in rheumatoid arthritis.

摘要

使用精密数字化仪测量右手第一掌骨头的标准化区域时,在测量者内部和测量者之间均获得了高度的可重复性。该仪器对每个数字化点的精度为0.127毫米。大约一个月间隔的测量者内部读数差异无显著差异。该方法操作相当简单,适用于近端指间关节等小关节。该方法可能在追踪类风湿关节炎关节损伤进展方面证明有用。

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1
Radiological changes in rheumatoid arthritis: measurement of area of juxta-articular bone as outcome event in clinical therapeutic trials of antirheumatic drugs.类风湿关节炎的放射学改变:在抗风湿药物临床治疗试验中,以关节周围骨面积测量作为结局事件
Clin Rheumatol. 1988 Dec;7(4):481-5.
2
Radiologic assessment as an outcome measure in rheumatoid arthritis.放射学评估作为类风湿性关节炎的一项结局指标。
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Increased metacarpal bone mass following 18 months of slow-acting antirheumatic drugs for rheumatoid arthritis.类风湿关节炎患者使用慢作用抗风湿药物18个月后掌骨骨量增加。
Br J Rheumatol. 1991 Apr;30(2):91-100. doi: 10.1093/rheumatology/30.2.91.
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Radiographic evaluation of the course of articular disease.关节疾病病程的影像学评估。
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Bone mass in patients with rheumatoid arthritis.类风湿关节炎患者的骨量
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[Exo- and endomarginal sclerosis of the metacarpal heads as a special reaction in chronic polyarthritis].[掌骨头的边缘外和边缘内硬化作为慢性多关节炎的一种特殊反应]
Z Rheumatol. 1988 Jul-Aug;47(4):209-12.
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[The carpus-metacarpus-index distance: a measurement for quantifying radiological lesions in rheumatoid polyarthritis. Comparison with Larsen's scores and Steinbrocker's index].[腕掌指数距离:类风湿性多关节炎放射学病变量化测量。与拉森评分和斯坦布鲁克指数的比较]
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A tangential radiographic projection for demonstrating involvement of metacarpal heads in rheumatoid arthritis.一种用于显示类风湿关节炎中掌骨头受累情况的切线位X线投照。
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Problems in the clinical evaluation of antirheumatic drugs.抗风湿药物临床评估中的问题。
Agents Actions Suppl. 1980;7:296-9.