Khechen Benjamin, Patel Dil V, Haws Brittany E, Cardinal Kaitlyn L, Guntin Jordan A, Ahn Junyoung, Singh Kern
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.
Clin Spine Surg. 2019 Dec;32(10):449-453. doi: 10.1097/BSD.0000000000000786.
This study was a retrospective cohort analysis.
This study aims to evaluate the concurrent validity of Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) domain as compared with legacy measures of patient-reported outcomes (PROs) among patients undergoing anterior cervical discectomy and fusion (ACDF).
As PROMIS becomes increasingly utilized, it is important to assess its validity among procedure-specific populations.
Patients undergoing a primary, 1-3 level ACDF were retrospectively identified from a prospectively maintained surgical registry. PROMIS PF and legacy PRO scores were obtained at preoperative, 6-week, 12-week, and 6-month postoperative visits. Legacy PROs included Neck Disability Index (NDI), Short Form-12 (SF-12) physical composite, Visual Analog Scale (VAS) neck pain, and VAS arm pain. Postoperative improvements in PROs were assessed using paired t tests. Correlations between PROMIS and legacy PROs were tested using Pearson correlation coefficient.
A total of 57 ACDF patients were analyzed. The mean preoperative PROMIS PF was 40.0±6.4. PROMIS PF significantly improved at 12-week and 6-month follow-up. NDI, VAS neck pain, and VAS arm pain scores demonstrated significant improvement at all postoperative time points. SF-12 scores only exhibited significant improvement at the 6-month follow-up visit. Significant correlations between PROMIS PF, NDI, and SF-12 were identified at all preoperative and postoperative time points. PROMIS PF exhibited strong correlations with VAS neck pain at postoperative time points, and a moderate correlation preoperatively.
Patients undergoing a primary 1-3 level ACDF experience significant improvements in PROMIS PF scores at 12-week and 6-month follow-up. Furthermore, PROMIS PF exhibits strong correlations to NDI and SF-12 at all preoperative and postoperative time points. These results suggest that PROMIS PF accurately measures PF and may be used in lieu of legacy PF instruments for patients undergoing ACDF.
本研究为回顾性队列分析。
本研究旨在评估患者报告结局测量信息系统（PROMIS）身体功能（PF）领域与传统患者报告结局（PRO）测量方法在前路颈椎间盘切除融合术（ACDF）患者中的同时效度。
随着PROMIS的应用越来越广泛，评估其在特定手术人群中的效度很重要。
从一个前瞻性维护的手术登记册中回顾性识别接受初次1 - 3节段ACDF的患者。在术前、术后6周、12周和6个月随访时获取PROMIS PF和传统PRO评分。传统PRO包括颈部残疾指数（NDI）、简明健康调查12项（SF - 12）身体综合评分、视觉模拟量表（VAS）颈部疼痛评分和VAS手臂疼痛评分。使用配对t检验评估PRO的术后改善情况。使用Pearson相关系数检验PROMIS与传统PRO之间的相关性。
共分析了57例ACDF患者。术前PROMIS PF的平均得分为40.0±6.4。在12周和6个月随访时，PROMIS PF显著改善。NDI、VAS颈部疼痛评分和VAS手臂疼痛评分在所有术后时间点均显示出显著改善。SF - 12评分仅在6个月随访时显示出显著改善。在所有术前和术后时间点，均发现PROMIS PF、NDI和SF - 12之间存在显著相关性。PROMIS PF在术后时间点与VAS颈部疼痛评分呈强相关，术前呈中度相关。
接受初次1 - 3节段ACDF的患者在12周和6个月随访时，PROMIS PF评分有显著改善。此外，在所有术前和术后时间点，PROMIS PF与NDI和SF - 12均呈强相关。这些结果表明，PROMIS PF能够准确测量身体功能，可用于替代ACDF患者的传统PF测量工具。
