García M P, Puig L, Pérez M, de Moragas J M
Servicio de Dermatología, Hospital San Pablo, Barcelona.
Med Cutan Ibero Lat Am. 1988;16(6):445-9.
Chronic mucocutaneous candidiasis is a chronic infection of mucoses, nails and skin due to Candida sp., that does not respond to standard treatment. We report on three patients with chronic mucocutaneous candidiasis in association with iron deficiency, IgA deficiency in one patient and adult onset in another. We review the clinical manifestations, the classification and the treatment of this disorder. The immunologic defects associated with chronic mucocutaneous candidiasis provide a model to study the mechanisms of defense of the host against fungal infections.
慢性黏膜皮肤念珠菌病是由念珠菌属引起的黏膜、指甲和皮肤的慢性感染,对标准治疗无反应。我们报告了3例慢性黏膜皮肤念珠菌病患者,其中1例伴有缺铁,1例伴有IgA缺乏,另1例为成人发病。我们回顾了这种疾病的临床表现、分类和治疗方法。与慢性黏膜皮肤念珠菌病相关的免疫缺陷为研究宿主抗真菌感染的防御机制提供了一个模型。