Squiquera L, Robledo M A, Martins C R, Díaz L A
Department of Dermatology, Johns Hopkins University, Baltimore, Maryland.
Med Cutan Ibero Lat Am. 1988;16(6):474-80.
The basement membranes are extracellular proteic matrixes involved mainly in cell-substrate interactions. The dermo-epidermal junction (DEJ) is defined as the region formed by the dermal pole of the basal cell layer, the intercellular spaces, the lamina densa or basal lamina and the acellular fibrous components of the papillary dermis. The functions of the DEJ are to bind the epithelia to the connective tissue, and to preserve the viability of the epidermis by means of connecting it to the dermis. which is in charge of providing the necessary nutrients for its normal proliferation. The purpose of the present communication is to provide a concise review of the recent knowledges about the ultrastructure of the DEJ, with special emphasis on its antigenic components.
基底膜是主要参与细胞与底物相互作用的细胞外蛋白质基质。真皮 - 表皮连接处(DEJ)被定义为由基底细胞层的真皮极、细胞间隙、致密板或基膜以及乳头层真皮的无细胞纤维成分形成的区域。DEJ的功能是将上皮与结缔组织结合,并通过将表皮连接到真皮来维持表皮的活力,真皮负责为其正常增殖提供必要的营养。本通讯的目的是简要回顾关于DEJ超微结构的最新知识,特别强调其抗原成分。