Institute of Chemistry Far Eastern Branch of the Russian Academy of Sciences, 159, prosp.100-letiya Vladivostoka, 690022 Vladivostok, Russia.
Institute of Chemistry Far Eastern Branch of the Russian Academy of Sciences, 159, prosp.100-letiya Vladivostoka, 690022 Vladivostok, Russia.
Carbohydr Polym. 2019 Apr 1;209:1-9. doi: 10.1016/j.carbpol.2018.12.094. Epub 2019 Jan 3.
Here we report a new simple method for fabrication of supermacroporous beads and monoliths via cross-linking of carboxyalkylated chitosan derivatives with hexamethylene diisocyanate in aqueous solution at subzero temperature. These materials provide high filtration rate and good mass-transfer that in combination with high binding capacity toward metal ions allows their application as a universal platform for fabrication of composite catalysts, sorbents, and metal-affine chromatography stationary phases. Using N-(2-carboxyethyl)chitosan (CEC), we have demonstrated that optimum chitosan carboxylation degree for cryogels synthesis is close to 1.0. Cu(II)-chelated CEC cryogels have shown high efficiency as metal-affinity sorbents for ciprofloxacin recovery. Co(II)-chelated CEC cryogels have been used for fabrication of Co(II) ferrocyanide-containing composite with the distribution coefficient for Cs of 140,000 ml/g and the adsorption capacity of ˜1 mmol/g. Composite Pd-catalysts supported on CEC cryogel provided tenfold higher reaction rate in 4-nitrophenol reduction in comparison with Pd-catalyst supported on chitosan beads.
在这里，我们报告了一种新的简单方法，通过在零下温度的水溶液中用六亚甲基二异氰酸酯交联羧烷基化壳聚糖衍生物来制备超大孔珠和整体材料。这些材料提供了高过滤速率和良好的传质，结合对金属离子的高结合能力，允许它们作为制备复合催化剂、吸附剂和金属亲和色谱固定相的通用平台。使用 N-(2-羧乙基)壳聚糖 (CEC)，我们证明了用于冷冻凝胶合成的壳聚糖最佳羧化度接近 1.0。Cu(II)螯合的 CEC 冷冻凝胶作为环丙沙星回收的金属亲和性吸附剂表现出高效率。Co(II)螯合的 CEC 冷冻凝胶已用于制备 Co(II)亚铁氰化物含量的复合材料，其对 Cs 的分配系数为 140,000 ml/g，吸附容量约为 1 mmol/g。负载在 CEC 冷冻凝胶上的复合 Pd 催化剂在 4-硝基苯酚还原反应中的反应速率比负载在壳聚糖珠上的 Pd 催化剂高十倍。
