Alasmari Amal Aboud, Hakeem Anadel Hassan, Bin Saleh Fatemah Saleh, Alsaigh Shahad Yousef, Al Ajroush Waleed, Layqah Laila Ali, Baharoon Salim Alawi
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Department of Dermatology, King Abdulaziz Medical City (KAMC), National Guard Health Affairs (NGHA), Riyadh, Saudi Arabia.
Dermatol Res Pract. 2019 Jan 13;2019:9891270. doi: 10.1155/2019/9891270. eCollection 2019.
Skin manifestations are common in hematology ward patients and can result from infection, malignancy, or chemotherapy. The purpose of this study was to identify the most common dermatological problems encountered in the adult hematology ward at King Abdullah Specialist Children Hospital (KASCH). This was retrospective chart review of 78 dermatology consultations based on electronic health records for all inpatients in hematology wards at KASCH between January 2016 and December 2017. Data were presented as mean ± SD for continuous variables. During the study period, a total of 1391 inpatients were referred to the dermatology department. A total of 403 (29.0%) referrals were from the internal medicine department and 78 (5.6%) were from the hematology department, six of which were rejected by the dermatology department. Almost all requests for referral were managed on the same or the next day with only two requests after 3 days. There were more female (n = 40; 51.3%) than male patients (n = 38; 48.7%) and the average age ± SD was 40.7 ± 19.8 years. Patients were diagnosed with a diverse range of hematological diseases. A total of 27 (35.1%) patients were diagnosed with acute myeloid leukemia. Overall, 98 differential diagnoses were made by dermatologists with only 26 being confirmed by skin biopsy. Eight (30.8%) patients were diagnosed with graft versus host disease confirmed by skin biopsy. The diagnoses were changed in 12 cases after skin biopsy. Several types of dermatitis were diagnosed in hematology ward patients including stasis dermatitis and contact dermatitis. The source of infection was not specified in most cases and the infection was treated empirically. Various dermatological disorders and cutaneous manifestations are observed in hematology inpatients with morbilliform drug eruption and graft versus host disease being the most common.
皮肤表现在血液科病房患者中很常见，可能由感染、恶性肿瘤或化疗引起。本研究的目的是确定阿卜杜拉国王专科医院（KASCH）成人血液科病房中最常见的皮肤科问题。这是一项基于KASCH血液科病房2016年1月至2017年12月所有住院患者电子健康记录的78例皮肤科会诊回顾性图表研究。连续变量的数据以平均值±标准差表示。在研究期间，共有1391名住院患者被转诊至皮肤科。共有403例（29.0%）转诊来自内科，78例（5.6%）来自血液科，其中6例被皮肤科拒绝。几乎所有转诊请求都在当天或次日得到处理，只有2例在3天后处理。女性患者（n = 40；51.3%）多于男性患者（n = 38；48.7%），平均年龄±标准差为40.7±19.8岁。患者被诊断患有多种血液系统疾病。共有27例（35.1%）患者被诊断为急性髓系白血病。总体而言，皮肤科医生做出了98种鉴别诊断，其中只有26种经皮肤活检得到证实。8例（30.8%）患者经皮肤活检确诊为移植物抗宿主病。12例患者在皮肤活检后诊断发生了改变。血液科病房患者诊断出几种类型的皮炎，包括淤积性皮炎和接触性皮炎。大多数情况下未明确感染源，感染按经验性治疗。血液科住院患者中观察到各种皮肤疾病和皮肤表现，其中麻疹样药疹和移植物抗宿主病最为常见。
