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静脉注射免疫球蛋白 G 在慢性炎症性脱髓鞘性多发性神经病患者中的应用:药物性盘状红斑狼疮的一个不常见病因。

Intravenous immunoglobulin G use in patients with chronic inflammatory demyelinating polyneuropathy: An uncommon cause of drug-induced discoid lupus erythematosus.

机构信息

Department of Dermatology, Temple University Hospital, Philadelphia, Pennsylvania, USA.

Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Australas J Dermatol. 2019 Aug;60(3):e208-e210. doi: 10.1111/ajd.12998. Epub 2019 Feb 7.

Abstract

Drug-induced chronic cutaneous lupus erythematosus, or drug-induced discoid lupus erythematosus, is a rare cutaneous phenomenon. Various medications have been associated with drug-induced discoid lupus erythematosus including fluorouracile agents, especially tegafur and uraciltegafur, and TNF-α antagonists such as infliximab or etanercept. Recent literature has described a case series of six patients receiving IgG immunoglobulin for chronic inflammatory demyelinating polyneuropathy with subsequent presentations of discoid lupus erythematosus. We present a patient with chronic inflammatory demyelinating polyneuropathy who developed discoid lupus erythematosus secondary to IgG immunoglobulin.

摘要

药物诱导的慢性盘状红斑狼疮,或药物诱导的盘状狼疮,是一种罕见的皮肤现象。各种药物与药物诱导的盘状红斑狼疮有关,包括氟尿嘧啶类药物,特别是替加氟和尿嘧啶替加氟,以及 TNF-α 拮抗剂,如英夫利昔单抗或依那西普。最近的文献描述了一组接受 IgG 免疫球蛋白治疗慢性炎症性脱髓鞘性多发性神经病的六例患者,随后出现盘状红斑狼疮。我们介绍了一位患有慢性炎症性脱髓鞘性多发性神经病的患者,由于 IgG 免疫球蛋白而继发盘状红斑狼疮。

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