Schmoch T, Al-Saeedi M, Hecker A, Richter D C, Brenner T, Hackert T, Weigand M A
Klinik für Anästhesiologie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
Chirurg. 2019 May;90(5):363-378. doi: 10.1007/s00104-019-0795-6.
Abdominal sepsis is the most severe form of abdominal infection. It is characterized by a dysregulated host response to infection leading to life-threatening organ failure or septic shock. The latter has a mortality of >40%. This article reviews the evidence on the strategic approach to treatment of patients with abdominal sepsis and septic shock. The focus is on the time-critical elements of diagnosis, anti-infective treatment and hemodynamic stabilization.
腹腔感染是腹部感染最严重的形式。其特征是宿主对感染的反应失调,导致危及生命的器官衰竭或感染性休克。后者的死亡率超过40%。本文综述了有关腹腔感染和感染性休克患者治疗策略的证据。重点是诊断、抗感染治疗和血流动力学稳定等时间紧迫的要素。