完美开胃菜：一种非叮咬式蚊子的药理学策略。
The Perfect Appetizer: A Pharmacological Strategy for a Non-biting Mosquito.
机构信息
Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor, Instituto René Rachou, Fiocruz, Belo Horizonte, MG, Brazil.
Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor, Instituto René Rachou, Fiocruz, Belo Horizonte, MG, Brazil.
出版信息
Cell. 2019 Feb 7;176(4):679-681. doi: 10.1016/j.cell.2019.01.032.
PMID:30735629
Abstract
New possibilities for vector-borne disease control are revealed by Duvall et al. (2019), who link host-seeking behavioral modulation in Aedes aegypti to neuropeptide Y (NPY)-like receptor 7. Small-molecule screening yields agonist compounds able to activate NPYLR7 and suppress attraction to hosts.
摘要
杜瓦尔等人（2019 年）揭示了控制虫媒传染病的新可能性，他们将埃及伊蚊的宿主寻找行为调节与神经肽 Y（NPY）样受体 7 联系起来。小分子筛选产生了能够激活 NPYLR7 并抑制对宿主吸引力的激动剂化合物。
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