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炎症性腹主动脉瘤的血管腔内修复:单中心经验

Endovascular Repair of Inflammatory Aortic Aneurysms: Experience in a Single Center.

作者信息

Cardaci Miguel Bouzas, Destraix Renaud, Van Houte Bernard, Vazquez Cesar

机构信息

Department of General, Vascular and Thoracic Surgery, Centre Hospitalière Regional du Val de Sambre Rue Chère-Voie, Sambreville, Belgium.

Department of Urology, Centre Hospitaliere Regional du Val de Sambre, Sambreville, Belgium.

出版信息

Ann Vasc Surg. 2019 Jul;58:255-260. doi: 10.1016/j.avsg.2018.10.046. Epub 2019 Feb 6.

Abstract

BACKGROUND

Inflammatory abdominal aortic aneurysm (IAAA) remained a rare cause of aneurysmal aortic disease, with incidences between 5% and 10%. The current treatment for IAAA consists of open surgical repair and endovascular aneurysm repair (EVAR). Avoiding an inflamed, fibrotic retroperitoneum is the driving force behind the desire to repair IAAA endovascularly. The latest published works confirm the promising results after EVAR for IAAA, but there is still a paucity of data regarding hydroureter and hydronephrosis. In this article, we describe our experience with 5 patients diagnosed with IAAA and treated by EVAR, of whom 3 presented with associated hydronephrosis.

METHODS

A retrospective review of our endovascular database identified five patients who underwent EVAR for IAAA. Unilateral ureteral involvement in the inflammatory process was seen in 3 patients, accompanied by secondary hydronephrosis. One patient presented retroperitoneal fibrosis with duodenal stenosis. Primary outcomes were primary technical success, aneurysm-related mortality, change in aneurysm size, perianeurysmal fibrosis (PAF), and hydronephrosis. Secondary outcomes were requirement for reintervention, progression/resolution of symptoms, and short-term clinical success.

RESULTS

Follow-up duration ranged from 3 to 61 months. No patients were lost to follow-up. Primary technical success was obtained in all patients. One patient died three months after the operation due to persistence of the duodenal stenosis in spite of subsequent endoscopic treatments and corticotherapy. The aneurysm sac progressively reduced in 4 patients and remained unchanged in one patient. PAF regressed in 2 patients, reduced in two, and remained unchanged in one patient. Hydronephrosis persisted in all three patients preoperatively diagnosed with this condition. No patient required subsequent intervention. Four patients had complete resolution of their symptoms at a follow-up visit at 1 month.

CONCLUSIONS

This series suggests that EVAR for IAAA is technically feasible, excludes the aneurysm effectively, and reduces PAF with an acceptable morbidity and mortality rate. EVAR does not seem to offer any benefits for hydronephrosis, and closer follow-up in patients presenting renal or ureter involvement treated by EVAR is necessary.

摘要

背景

炎性腹主动脉瘤(IAAA)仍然是动脉瘤性主动脉疾病的罕见病因,发病率在5%至10%之间。IAAA目前的治疗方法包括开放手术修复和血管腔内动脉瘤修复(EVAR)。避免炎症性、纤维化的腹膜后腔是希望通过血管腔内修复IAAA的主要驱动力。最新发表的研究证实了EVAR治疗IAAA后取得的良好结果,但关于输尿管积水和肾盂积水的数据仍然很少。在本文中,我们描述了5例诊断为IAAA并接受EVAR治疗的患者的经验,其中3例伴有肾盂积水。

方法

对我们的血管腔内数据库进行回顾性分析,确定了5例接受EVAR治疗IAAA的患者。3例患者单侧输尿管受累于炎症过程,伴有继发性肾盂积水。1例患者出现腹膜后纤维化伴十二指肠狭窄。主要结局指标为初次技术成功率、动脉瘤相关死亡率、动脉瘤大小变化、动脉瘤周围纤维化(PAF)和肾盂积水。次要结局指标为再次干预的必要性、症状的进展/缓解情况以及短期临床成功率。

结果

随访时间为3至61个月。无患者失访。所有患者均取得初次技术成功。1例患者术后3个月因尽管后续进行了内镜治疗和皮质激素治疗但十二指肠狭窄持续存在而死亡。4例患者的动脉瘤囊逐渐缩小,1例患者保持不变。2例患者的PAF消退,2例减轻,1例患者保持不变。术前诊断为肾盂积水的3例患者中,肾盂积水均持续存在。无患者需要后续干预。4例患者在1个月的随访中症状完全缓解。

结论

本系列研究表明,EVAR治疗IAAA在技术上是可行的,能有效排除动脉瘤,并以可接受的发病率和死亡率降低PAF。EVAR似乎对肾盂积水无任何益处,对于接受EVAR治疗的肾或输尿管受累患者,有必要进行密切随访。

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