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多囊卵巢综合征、微生物组学以及为何你应该在时间上稍微自私一点。

Polycystic ovary syndrome, microbiomics and why you should be a little selfish with your time.

作者信息

Azziz Ricardo

机构信息

a Georgia Regents University, Augusta, GA, USA.

出版信息

Expert Rev Endocrinol Metab. 2013 Jul;8(4):329-331. doi: 10.1586/17446651.2013.811862.

Abstract

Interview by Rona Williamson Ricardo Azziz, MD, MPH, MBA, is Professor of Obstetrics and Gynecology (Ob/Gyn), Medicine and Medical Humanities, and President, at Georgia Regents University and CEO of the Georgia Regents Health System, Augusta, GA, USA. Georgia Regents University is one of Georgia's four public comprehensive research universities, with recognized strengths in the health sciences, and including the state's only academic health center. Formerly, Dr. Azziz served as Deputy Director for the Clinical and Translational Sciences Institute, Assistant Dean for Clinical and Translational Sciences, Vice-Chair of the Department of Ob/Gyn and co-Director of the Reproductive Endocrinology Fellowship Training Program at UCLA; and Director of the Center for Androgen-Related Disorders and Chair, Department of Ob/Gyn at the Cedars-Sinai Medical Center, Los Angeles, CA, USA. Dr. Azziz is an internationally recognized authority on androgen excess (disorders related to excess male hormones) in women, having published over 400 original peer-reviewed articles, book chapters and reviews. He has been funded by the NIH, among other entities, for his research for more than 25 years. Dr. Azziz's laboratory has contributed significantly to the field of androgen excess research. This has included: establishing the populational prevalences and economic impact of the polycystic ovary syndrome (PCOS), the single most common form of androgen excess, idiopathic hirsutism and nonclassic adrenal hyperplasia, the most common form of an inherited defect of adrenal function in man; determining the familial risk for PCOS and elucidating some of the candidate genes that play a role in the disorder; identifying many of the molecular, genetic and physiologic mechanism(s) resulting in adrenal androgen excess in PCOS; and beginning to identify the unique defects in the molecular action of fat tissue in PCOS. In 2000, he received the President's Achievement Award of the Society for Gynecologic Investigation for his research, and in that same year, he founded the Androgen Excess and PCOS Society, the only worldwide organization dedicated to promoting education and research in these disorders, where he currently serves as Senior Executive Director. His passion and focus for improving the care of women affected by reproductive endocrine disorders, and in particular androgen excess, has been recognized widely, including being named as one of, 'America's Top Doctors' (Castle Connolly Medical Ltd, New York, NY, USA) from 2001 to present, and being recognized by various other lay press and patient-focused venues. Dr. Azziz' musings on leadership, academics and healthcare can be seen at his blog site 'Sculpting in Clay' and now the Huffington Post .

摘要

罗娜·威廉姆森的访谈 里卡多·阿齐兹医学博士、公共卫生硕士、工商管理硕士,是美国佐治亚州奥古斯塔市佐治亚州立大学医学院妇产科、医学与医学人文教授兼院长,以及佐治亚州立大学健康系统首席执行官。佐治亚州立大学是佐治亚州四所公立综合性研究型大学之一,在健康科学领域实力公认,包括该州唯一的学术健康中心。此前,阿齐兹博士曾担任加州大学洛杉矶分校临床与转化科学研究所副主任、临床与转化科学助理院长、妇产科副主任以及生殖内分泌学 fellowship 培训项目联合主任;还曾担任美国加利福尼亚州洛杉矶市雪松西奈医疗中心雄激素相关疾病中心主任及妇产科主任。阿齐兹博士是国际公认的女性雄激素过多(与男性激素过多相关的疾病)权威,发表了 400 多篇经同行评审的原创文章、书籍章节和评论。25 多年来,他的研究一直获得美国国立卫生研究院等机构的资助。阿齐兹博士的实验室对雄激素过多研究领域做出了重大贡献。这包括:确定多囊卵巢综合征(PCOS,最常见的雄激素过多形式)、特发性多毛症和非经典肾上腺皮质增生(男性肾上腺功能遗传性缺陷最常见的形式)的人群患病率和经济影响;确定 PCOS 的家族风险并阐明一些在该疾病中起作用的候选基因;识别导致 PCOS 患者肾上腺雄激素过多的许多分子、遗传和生理机制;以及开始识别 PCOS 患者脂肪组织分子作用中的独特缺陷。2000 年,他因研究获得妇科研究协会主席成就奖,同年,他创立了雄激素过多与 PCOS 协会,这是全球唯一致力于促进这些疾病教育和研究的组织,他目前担任高级执行董事。他对改善受生殖内分泌疾病影响的女性,尤其是雄激素过多女性的护理的热情和专注得到了广泛认可,包括从 2001 年至今被评为“美国顶级医生”(美国纽约州纽约市城堡康诺利医疗有限公司),并在其他各种大众媒体和以患者为中心的场合获得认可。阿齐兹博士关于领导力、学术和医疗保健的思考可以在他的博客“黏土雕塑”以及现在的《赫芬顿邮报》上看到。

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