Nobre Miguel de Araújo, Sezinando Ana, Fernandes Inês, Maló Paulo
Research and Development Department, Maló Clinic, 1600-042 Lisbon, Portugal.
Dentistry Department, Maló Clinic, 4100-130 Porto, Portugal.
J Clin Med. 2019 Feb 7;8(2):203. doi: 10.3390/jcm8020203.
There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries.
This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randomly sampled from the study population at baseline), followed for 3 years. The risk ratio (RR) for each potential predictor was estimated using a logistic regression model. The level of significance was 5%.
The risk model for dental caries included the predictors: "presence of bacterial plaque/calculus" (RR = 4.1), "restorations with more than 5 years" (RR = 2.3), ">8 teeth restored" (RR = 2.0), "history/active periodontitis" (RR = 1.7) and "presence of systemic condition" (RR = 1.4). The risk model discrimination (95% confidence interval) was 0.78 (0.73; 0.82) ( < 0.001, C-statistic). Patients were distributed into three risk groups based on the pre-analysis risk (54%): low risk (<half the pre-analysis risk; caries incidence = 6.8%), moderate risk (half-to-less than the pre-analysis risk; caries incidence = 20.4%) and high risk (≥the pre-analysis risk; caries incidence = 27%).
The present study estimated a simple risk score for prediction of dental caries retrieved from a risk algorithm with good discrimination.
龋病研究中需要风险预测工具。本研究旨在评估和评价用于预测龋齿的风险评分。
本病例队列研究纳入了177例(患有龋齿)病例和220例对照(在基线时从研究人群中随机抽取)的随机样本,随访3年。使用逻辑回归模型估计每个潜在预测因素的风险比(RR)。显著性水平为5%。
龋齿风险模型包括以下预测因素:“存在菌斑/牙石”(RR = 4.1)、“修复时间超过5年”(RR = 2.3)、“修复牙齿超过8颗”(RR = 2.0)、“有牙周炎病史/活动期”(RR = 1.7)和“存在全身疾病”(RR = 1.4)。风险模型的辨别力(95%置信区间)为0.78(0.73;0.82)(<0.001,C统计量)。根据分析前风险将患者分为三个风险组(54%):低风险(<分析前风险的一半;龋齿发病率 = 6.8%)、中度风险(分析前风险的一半至小于分析前风险;龋齿发病率 = 20.4%)和高风险(≥分析前风险;龋齿发病率 = 27%)。
本研究评估了一种简单的风险评分,用于从具有良好辨别力的风险算法中预测龋齿。