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用于临床环境中预测成年患者龋齿的风险评分

Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting.

作者信息

Nobre Miguel de Araújo, Sezinando Ana, Fernandes Inês, Maló Paulo

机构信息

Research and Development Department, Maló Clinic, 1600-042 Lisbon, Portugal.

Dentistry Department, Maló Clinic, 4100-130 Porto, Portugal.

出版信息

J Clin Med. 2019 Feb 7;8(2):203. doi: 10.3390/jcm8020203.

Abstract

BACKGROUND

There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries.

MATERIALS AND METHODS

This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randomly sampled from the study population at baseline), followed for 3 years. The risk ratio (RR) for each potential predictor was estimated using a logistic regression model. The level of significance was 5%.

RESULTS

The risk model for dental caries included the predictors: "presence of bacterial plaque/calculus" (RR = 4.1), "restorations with more than 5 years" (RR = 2.3), ">8 teeth restored" (RR = 2.0), "history/active periodontitis" (RR = 1.7) and "presence of systemic condition" (RR = 1.4). The risk model discrimination (95% confidence interval) was 0.78 (0.73; 0.82) ( < 0.001, C-statistic). Patients were distributed into three risk groups based on the pre-analysis risk (54%): low risk (<half the pre-analysis risk; caries incidence = 6.8%), moderate risk (half-to-less than the pre-analysis risk; caries incidence = 20.4%) and high risk (≥the pre-analysis risk; caries incidence = 27%).

CONCLUSIONS

The present study estimated a simple risk score for prediction of dental caries retrieved from a risk algorithm with good discrimination.

摘要

背景

龋病研究中需要风险预测工具。本研究旨在评估和评价用于预测龋齿的风险评分。

材料与方法

本病例队列研究纳入了177例(患有龋齿)病例和220例对照(在基线时从研究人群中随机抽取)的随机样本,随访3年。使用逻辑回归模型估计每个潜在预测因素的风险比(RR)。显著性水平为5%。

结果

龋齿风险模型包括以下预测因素:“存在菌斑/牙石”(RR = 4.1)、“修复时间超过5年”(RR = 2.3)、“修复牙齿超过8颗”(RR = 2.0)、“有牙周炎病史/活动期”(RR = 1.7)和“存在全身疾病”(RR = 1.4)。风险模型的辨别力(95%置信区间)为0.78(0.73;0.82)(<0.001,C统计量)。根据分析前风险将患者分为三个风险组(54%):低风险(<分析前风险的一半;龋齿发病率 = 6.8%)、中度风险(分析前风险的一半至小于分析前风险;龋齿发病率 = 20.4%)和高风险(≥分析前风险;龋齿发病率 = 27%)。

结论

本研究评估了一种简单的风险评分,用于从具有良好辨别力的风险算法中预测龋齿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9639/6406458/b05bd053ab54/jcm-08-00203-g001.jpg

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