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Intermittent intraarterial infusion therapy with PGE1 in patients with severe claudication--results of a randomized prospective double blind study.

作者信息

Caspary L, Creutzig A, Radeke U, Specht S, Alexander K

机构信息

Abteilung Angiologie, Medizinische Hochschule, Hannover, FRG.

出版信息

Biomed Biochim Acta. 1988;47(10-11):S307-10.

PMID:3073766
Abstract

In a randomized prospective double blind study, intraarterial infusion therapy with prostaglandin E1 (PGE) was tested against infusion therapy with energy rich phosphates (ERP) in 40 patients with severe claudication. During the treatment period of three weeks, a significant increase of the painfree (PWD) and maximal walking distance (MWD) was observed. The improvement of PWD was of clinical relevance (PGE: 60----195 m; ERP: 69----170 m; p less than 0.001) and persisted during a 36 week post treatment observation period. The differences between the two drugs were not significant but showed a tendency in favour of the PGE therapy.

摘要

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