Department of Otolaryngology - Head and Neck Surgery, Louisiana State University Health Science Center - New Orleans, New Orleans, Louisiana.
Department of Otolaryngology - Head and Neck Surgery, Stanford University, Stanford, California.
Head Neck. 2019 Apr;41(4):930-939. doi: 10.1002/hed.25424. Epub 2019 Feb 9.
Critical review of current head and neck reconstructive practices as related to free flap donor sites and their impact on clinical outcomes and cost.
Retrospective multicenter review of free tissue transfer reconstruction of head and neck defects (n = 1315). Variables reviewed: defect, indication, T classification, operative duration, and complications. A convenience sample was selected for analysis of overall (operative and inpatient admission) charges per hospitalization (n = 400).
Mean charges of hospitalization by donor tissue: radial forearm free flap (RFFF) $127 636 (n = 183), osteocutaneous RFFF (OCRFFF) $125 456 (n = 70), anterior lateral thigh $133 781 (n = 54), fibula $140 747 (n = 42), latissimus $208 890 (n = 24), rectus $169 637 (n = 18), scapula $128 712 (n = 4), and ulna $110 716 (n = 5; P = .16). Mean operative times for malignant lesions stratified by T classification: 6.9 hours (±25 minutes) for T1, 7.0 hours (±16 minutes) for T2, 7.3 hours (±17 minutes) for T3, and 7.8 hours (±11 minutes) for T4 (P < .0001). Complications correlated with differences in mean charges: minor surgical ($123 720), medical ($216 387), and major surgical ($169 821; P < .001). Operations for advanced malignant lesions had higher mean charges: T1 lesions ($106 506) compared to T2/T3 lesions ($133 080; P = .03) and T4 lesions ($142 183; P = .02). On multivariate analysis, the length of stay, operative duration, and type a postoperative complication were factors affecting overall charges for the hospitalization (P < .018).
Conclusion: The RFFF and OCRFFF had the lowest complication rates, length of hospitalization, duration of operation, and mean charges of hospitalization. Advanced stage malignant disease correlated with increased hospitalization length, operative time, and complication rates resulting in higher hospitalization charges.
对头颈重建中游离皮瓣供区的相关实践进行批判性回顾,并评估其对临床结果和成本的影响。
回顾性分析 1315 例头颈部缺陷游离组织移植重建患者的临床资料。分析的变量包括:缺陷类型、适应证、T 分类、手术时间和并发症。选择方便样本对 400 例患者的总体(手术和住院期间)住院费用进行分析。
不同供区组织游离皮瓣的住院费用均值:桡侧前臂游离皮瓣(RFFF)$127636(n=183)、骨-肌皮瓣游离皮瓣(OCRFFF)$125456(n=70)、前外侧大腿游离皮瓣$133781(n=54)、腓骨游离皮瓣$140747(n=42)、背阔肌游离皮瓣$208890(n=24)、腹直肌游离皮瓣$169637(n=18)、肩胛骨游离皮瓣$128712(n=4)、尺骨游离皮瓣$110716(n=5;P=0.16)。根据 T 分类分层的恶性肿瘤手术时间均值:T1 为 6.9 小时(±25 分钟),T2 为 7.0 小时(±16 分钟),T3 为 7.3 小时(±17 分钟),T4 为 7.8 小时(±11 分钟)(P<0.0001)。并发症与平均费用差异相关:小手术($123720)、内科($216387)和大手术($169821;P<0.001)。晚期恶性病变的手术费用较高:T1 病变($106506)低于 T2/T3 病变($133080;P=0.03)和 T4 病变($142183;P=0.02)。多变量分析显示,住院时间、手术时间和术后 A 型并发症是影响住院总费用的因素(P<0.018)。
桡侧前臂游离皮瓣和骨-肌皮瓣游离皮瓣的并发症发生率、住院时间、手术时间和住院费用最低。晚期恶性疾病与住院时间延长、手术时间延长和并发症发生率增加相关,导致住院费用增加。