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[跨膜电势作为生物膜功能活性的调节因子]

[Transmembrane electric potential as a regulator of functional activity of biomembranes].

作者信息

Konev S V, Kapler G V

出版信息

Biofizika. 1988 Nov-Dec;33(6):1018-22.

PMID:3073810
Abstract

The role of the transmembrane electric potential difference in producing structural tension of biological membranes is analysed. A suggestion is made that delta psi can optimize conditions of protein-protein interactions by ordering the membrane lipid. For energy-coupling membranes this makes it possible to explain the dependence of ATP synthesis on both electron transport and delta psi in terms of local bioenergetic coupling. The energized biomembrane is considered as a self-supporting structure, delta psi being a regulator of efficiency of molecular machines performing different membrane functions, including energization as well.

摘要

分析了跨膜电势差在产生生物膜结构张力中的作用。有人提出,δψ可以通过使膜脂有序排列来优化蛋白质-蛋白质相互作用的条件。对于能量耦合膜,这使得从局部生物能量耦合的角度来解释ATP合成对电子传递和δψ的依赖性成为可能。充满能量的生物膜被视为一种自支撑结构,δψ是执行不同膜功能(包括能量供应)的分子机器效率的调节器。

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