Department of Otorhinolaryngology, University Hospital Split, Spinciceva 1, 21000 Split, Croatia.
Department of Neuroscience, University of Lethbridge, EP1249 Exploration Place 4401 University Drive, Lethbridge, AB, Canada.
J Clin Epidemiol. 2019 May;109:111-116. doi: 10.1016/j.jclinepi.2019.01.012. Epub 2019 Feb 6.
To analyze data sharing practices among authors of randomized controlled trials (RCTs) published in seven high-ranking anesthesiology journals from 2014 to 2016.
We analyzed data sharing statements in 619 included RCTs and contacted their corresponding authors, asking them to share de-identified raw data from trial.
Of the 86 (14%) authors who responded to our query for data sharing, only 24 (4%) provided the requested data. Only one of those 24 had a data sharing statement in the published manuscript. Only 24 (4%) of manuscripts contained statements suggesting a willingness to share trial data; only one of those authors actually shared data. There was no difference in proportion of data sharing between studies with commercial and nonprofit funding. Among the 62 authors who refused to provide data, reasons were seldom provided. When reasons were provided, common themes included issues regarding data ownership and participant privacy. Only one of the seven analyzed journals encouraged authors toward data sharing.
Willingness to share data among anesthesiology RCTs is very low. To achieve widespread availability of de-identified trial data, journals should request their publication, as opposed to only encouraging authors to do so.
分析 2014 年至 2016 年发表在七本高排名麻醉学期刊上的随机对照试验（RCT）作者的数据共享实践。
我们分析了 619 项纳入 RCT 的数据共享声明，并联系了相应的作者，要求他们分享试验的去识别原始数据。
在对我们的数据共享查询做出回应的 86 名作者中（14%），只有 24 名（4%）提供了请求的数据。这 24 人中只有 1 人在已发表的手稿中有数据共享声明。只有 24 篇（4%）手稿中包含了愿意分享试验数据的声明；其中只有一位作者实际上分享了数据。有商业和非营利性资助的研究之间的数据共享比例没有差异。在 62 名拒绝提供数据的作者中，很少提供拒绝的原因。当提供原因时，常见的主题包括数据所有权和参与者隐私问题。在分析的七个期刊中，只有一个期刊鼓励作者进行数据共享。
麻醉学 RCT 中数据共享的意愿非常低。为了广泛提供去识别的试验数据，期刊应要求作者提供数据，而不仅仅是鼓励作者这样做。
