Therapeutic Radiology, Yale University School of Medicine, New Haven, CT.
Michigan State University College of Human Medicine, East Lansing, MI.
Urol Oncol. 2019 Sep;37(9):619-627. doi: 10.1016/j.urolonc.2019.01.015. Epub 2019 Feb 7.
For prostate cancer radiation therapy, daily sessions spanning approximately 2 months has been considered the standard of care for patients managed with curative intent. In recent years, data has emerged which supports the use of higher dose per fraction schemes leading to a reduced duration of treatment. This form of radiation-generally termed moderate hypofractionation or stereotactic body radiation therapy-increasingly appears to be a safe and effective alternative to the conventional course. This review summarizes salient data from the literature on outcomes, toxicities, and future directions for this innovative strategy of care.
对于前列腺癌放射治疗，每天进行大约 2 个月的治疗被认为是对有治愈意图的患者的标准治疗。近年来，出现的数据支持使用更高的分割剂量方案，从而缩短治疗时间。这种形式的放射治疗——通常称为中度适形分割或立体定向体部放射治疗——似乎越来越成为传统治疗方法的安全有效的替代方法。本综述总结了文献中关于该创新治疗策略的结果、毒性和未来方向的重要数据。
