Laboratorio de Investigación en Agentes Antibacterianos, Universidad de Concepción, Departamento de Microbiología, Facultad de Ciencias Biológicas, Concepción, Chile; Laboratorio Central, Hospital Regional Dr. Guillermo Grant Benavente, Concepción, Chile.
Laboratório de Pesquisa em Infecção Hospitalar, Instituto Oswaldo Cruz-FIOCRUZ, Rio de Janeiro, Brazil.
Int J Infect Dis. 2019 Apr;81:28-30. doi: 10.1016/j.ijid.2019.01.051. Epub 2019 Feb 7.
Carbapenemase-producing Enterobacteriaceae have rapidly disseminated worldwide and can colonize patients in healthcare centers. As in Chile the first isolations of NDM-1 and OXA-370 carbapenemases were related with a patient arriving from Brazil, the genetic relatedness of Klebsiella pneumoniae strains producers of these enzymes and isolated in both countries was assessed. PFGE analyses revealed that the isolates were clonally related, illustrating how travel contributes to the spread of multidrug-resistant microorganisms. In addition, the occurrence of three different carbapenemases in three different K. pneumoniae strains isolated from a single patient is described.
产碳青霉烯酶肠杆菌科已在全球范围内迅速传播，并可定植于医疗机构中的患者。在智利，首例 NDM-1 和 OXA-370 碳青霉烯酶的分离株与一位来自巴西的患者有关，因此评估了在这两个国家分离的产这些酶的肺炎克雷伯菌的遗传相关性。PFGE 分析表明，这些分离株具有克隆相关性，说明了旅行如何促进了多药耐药微生物的传播。此外，还描述了从一位患者中分离的三个不同的肺炎克雷伯菌菌株中存在三种不同的碳青霉烯酶。
