Jha Beena, Bhattarai Sabina, Sapkota Jyotshna, Sharma Manisha, Bhatt Chandra Prakash
Department of Microbiology, Kathmandu Medical College, Duwakot, Bhaktapur and Teaching Hospital, Nepal.
Department of Dermatology and venereology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal.
J Nepal Health Res Counc. 2019 Jan 28;16(41):434-437.
Dermatophytosis are the most common types of cutaneous fungal infection seen in human and animals affecting skin, hair and nails caused by dermatophytes. The diagnosis of dermatophytes is based on the clinical observation and laboratory diagnosis by direct microscopic examination and fungal cultures. The present study is undertaken to isolate different type of dermatophytes causing fungal infection.
A prospective cross-sectional study design was used in a total of 90 clinically suspected cases of dermatophytic infection attending the out patient department of Kathmandu Medical College and Teaching hospital (KMCTH). Skin scraping, hair and nail samples were collected from the patients and were processed by direct microscopy and culture using standard protocol. Dermatophytes were identified based on the microscopic arrangement of microconidia and macroconidia.
Dermatophytosis was more common in the age group of 21-40 years and was more predominant among male with male to female ratio of 1.7: 1. Among the total clinically suspected cases of dermatophytosis, 53 were positive in direct microscopy and only a total of 20 were positive by culture. Most common clinical type observed in our study was Tinea corporis(25%) followed by Tinea cruris. Trichophyton rubrum(50%) was the commonest aetiological agent in majority of clinical types followed by Trychophyton mentagrophytes(35%).
The study highlighted T. corporis followed by T. cruris and T. unguim as the most common clinical pattern of dermatophytosis with a male predominance and 21-40 years being the most affected age group. T. rubram was the most common aetiological agent causing dermatophytosis.
皮肤癣菌病是人和动物中最常见的皮肤真菌感染类型，由皮肤癣菌引起，可影响皮肤、毛发和指甲。皮肤癣菌的诊断基于临床观察以及直接显微镜检查和真菌培养的实验室诊断。本研究旨在分离引起真菌感染的不同类型皮肤癣菌。
采用前瞻性横断面研究设计，对加德满都医学院和教学医院（KMCTH）门诊的90例临床疑似皮肤癣菌感染病例进行研究。从患者处采集皮肤刮屑、毛发和指甲样本，并按照标准方案通过直接显微镜检查和培养进行处理。根据小分生孢子和大分生孢子的显微镜排列来鉴定皮肤癣菌。
皮肤癣菌病在21 - 40岁年龄组中更为常见，男性更为突出，男女比例为1.7:1。在所有临床疑似皮肤癣菌病病例中，直接显微镜检查有53例呈阳性，而培养仅有20例呈阳性。本研究中观察到的最常见临床类型是体癣（25%），其次是股癣。红色毛癣菌（50%）是大多数临床类型中最常见的病原体，其次是须癣毛癣菌（35%）。
该研究强调体癣、股癣和甲癣是皮肤癣菌病最常见的临床类型，男性居多，21 - 40岁是受影响最严重的年龄组。红色毛癣菌是引起皮肤癣菌病最常见的病原体。
