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担忧行为对广泛性焦虑症诊断的作用

The Contribution of Worry Behaviors to the Diagnosis of Generalized Anxiety Disorder.

作者信息

Brown Timothy A, Tung Esther S

机构信息

Center for Anxiety & Related Disorders, Department of Psychological and Brain Sciences, Boston University, Boston, MA.

出版信息

J Psychopathol Behav Assess. 2018 Dec;40(4):636-644. doi: 10.1007/s10862-018-9683-5. Epub 2018 May 10.

Abstract

Worry behaviors (i.e., overt acts to avoid or cope with worry-induced distress) have been recognized as being important in the psychopathology and treatment of generalized anxiety disorder (GAD). This study evaluated the worry behaviors criterion proposed for GAD, but was ultimately not adopted due to insufficient evidence. In 800 outpatients with emotional disorders (366 with GAD), most patients with GAD (92.6%) met the proposed worry behaviors criterion, which was at a rate significantly higher than other patient groups (e.g., patients with mood disorders). Patients who met the worry behaviors criterion had more severe GAD than patients who did not. The worry behaviors criterion, and 3 of its 4 constituent behaviors, were associated with no better than "fair" interrater reliability. Diagnostic reliability of GAD was not improved in cases where both interviewers agreed the worry behaviors criterion was met. The worry behaviors criterion significantly predicted GAD holding core GAD features constant (e.g., excessive worry), but this contribution was weak and did not appreciably improve the classification accuracy of GAD diagnostic status. Mixed support was obtained for the discriminant validity of the worry behaviors criterion in relation to mood disorders. Raising the proposed threshold of the criterion (requiring 2 instead of 1 behaviors) did not result in a substantial improvement in reliability, prediction, and classification accuracy. Although additional research is warranted (e.g., importance of worry behaviors in the treatment and natural course of GAD), the results raise questions about the role of worry behaviors in the diagnostic classification of GAD.

摘要

担忧行为(即避免或应对由担忧引发的痛苦的公开行为)已被认为在广泛性焦虑症(GAD)的精神病理学和治疗中具有重要意义。本研究对针对GAD提出的担忧行为标准进行了评估,但由于证据不足,该标准最终未被采纳。在800名患有情绪障碍的门诊患者(366名患有GAD)中,大多数GAD患者(92.6%)符合提出的担忧行为标准,这一比例显著高于其他患者群体(如情绪障碍患者)。符合担忧行为标准的患者比不符合的患者患有更严重的GAD。担忧行为标准及其4个构成行为中的3个,其评定者间信度不高于“一般”。在两位访谈者都认为符合担忧行为标准的病例中,GAD的诊断信度并未提高。在保持GAD核心特征(如过度担忧)不变的情况下,担忧行为标准能显著预测GAD,但这种作用较弱,并未明显提高GAD诊断状态的分类准确性。对于担忧行为标准相对于情绪障碍的判别效度,研究结果提供了混合性支持。提高该标准提议的阈值(要求有2种而非1种行为)并未在信度、预测和分类准确性方面带来实质性改善。尽管有必要进行更多研究(如担忧行为在GAD治疗和自然病程中的重要性),但研究结果对担忧行为在GAD诊断分类中的作用提出了质疑。

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